Agenda Overview

 

Lisbon, 29 - 31 October 2018

Schedule

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Oct 2908:40
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Opening discussion: Vaccine discovery and challenges in translating research into vaccine products

Keynotes
  • Covering major challenges in translational phase of bench to clinic including scale up challenges and safety for ph1 trials
  • Engaging stakeholders to want to push forward
  • Addressing the scientific roadblocks preventing more vaccines against common and neglected infectious diseases with high mortality rates
  • A new strategy: Can we continue to be dependent on industry for process development and advanced clinical development, especially for products destined for LMICs?
Oct 2909:40
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Expectations and reality of cancer vaccines working: The impact of combinational approaches to immune-oncology therapies and more targeted responses

Keynotes
  • Development of novel therapies against cancer, based on vaccines, neoantigens, checkpoint inhibitors and adoptive T cell transfer
  • How close are these to actually treating patients? The translation of innovative therapeutic approaches into early clinical trials
  • Optimal methods of antigen delivery for vaccinesin dendritic cells
Dr Thomas G. Evans, VaccitechUnited Kingdom
Dr Daniel Speiser, Head of Clinical Tumour Biology and Immunotherapy Group, University of LausanneSwitzerland
Professor Dirk Jager, Managing Director, University Hospital of HeidelbergGermany
Dr Laszlo Radvanyi, Senior Vice President, Senior Scientific Advisor, EMD SeronoUnited States
Oct 2911:40
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Interactive Roundtables

Keynotes
2 x Interactive Roundtables: 11:40 to 12:25 (rotation one) and 12:25 to 13:10 (rotation two). If you have not filled out the survey please choose them on the sign-up sheets located outside of the exhibition hall/or ask registration for more information. Choose two x 45 min long roundtables for these interactive discussions with like-minded peers
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Animal component free media: What’s critical?

Keynotes
To be updated
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Applications of CRISPR technology in new global challenges affecting livestock

Keynotes
Dr Christine Tait-Burkard, Assistant Professor, The Roslin InstituteUnited Kingdom
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DNA, live vectors, adjuvanted vaccines. 30 years later, are they inter changeable or is there a specific use for each?

Keynotes
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Intradermal delivery of therapeutic vaccines – benefits and challenges

Keynotes
To be updated
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New ways of “universalizing” vaccine production: The DiViNe project

Keynotes
Dr Manuel Carrondo, Vice President, I.B.E.T.Portugal
Mikkel Nissum, Technical Development Leader, GSK VaccineItaly
Jonas Anders, Associate Director - Sales Development Purification Eastern, Merck GroupGermany
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The regulators relationship with Challenge Studies; yesterday, today & tomorrow

Keynotes
To be updated
Bruno Speder, Head of Clinical Regulatory Affairs, SGS – Life Science ServicesBelgium
Dr Adrian Wildfire, Project Director - Infectious Diseases & Viral Infection Unit, SGS Life Science ServicesSwitzerland
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Vaccine Characterisation and Release – In-vivo vs in-vitro and the use of 3Rs (Reduction, refinement, replacement)

Keynotes
Dr Bassam Hallis, Head of Pre Clinical Development and General Project Manager, Public Health EnglandUnited Kingdom
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Vaccine manufacturing process development and production

Keynotes
Moderated bySenior representative, Sartorius
Oct 2914:40
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Chair’s opening remarks

Veterinary Vaccines
Oct 2914:45
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When will a universal flu vaccines be within reach?

Respiratory Vaccines
Oct 2914:45
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Designing effective patient-specific neoantigen cancer vaccines

Immuno-Oncology Profiling
  • Challenges and opportunities in developing a new form of personalized immunotherapy
  • Manufacturing & Clinical updates on Autosynvax™
  • Feasibility of evoking immune responses with reliability and potency
Oct 2914:45
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How can ZAPI act as an interface between human and veterinary vaccine development so they can learn from each other?

Veterinary Vaccines
  • Can common requirements be developed and is there a need?
  • The use of novel platform technologies for vaccine production
  • Regulatory innovation for novel vaccine technologies: A 2-stage quality process from veterinary to human vaccines
Dr Jean-Christophe Audonnet, Senior Director, Research Strategy and Key Alliances, Bio R&D and Coordinatior at ZAPI, MerialFrance
Oct 2914:45
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Smarter vaccine designs using synthetic virus-like particle technology and structurally optimised antigens

New Vaccine Technology
Oct 2915:00
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MVA-VLP as a Plug and Play platform for development of safe and effective single dose vaccines for Emerging Infectious Diseases, Preclinical data for Zika, Ebola and Lassa as examples

New Vaccine Technology
Dr Farshad Guirakhoo, CSO, GeoVax, Inc.United States
Oct 2915:15
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Update on the most advanced universal flu vaccine candidate – 6 completed clinical trials

Respiratory Vaccines
Oct 2915:15
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Cancer Immunotherapy: Individualized mRNA-based Vaccines for the Treatment of Cancer

Immuno-Oncology Profiling
Oct 2915:30
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Phase IIb trial of a novel influenza vaccine regimen for the over 65s Dr Sarah Gilbert, Professor of Vaccinology, University of Oxford

Respiratory Vaccines
Oct 2915:30
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Oct 2915:30
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Developments for Tick Borne Encephalitis vaccine

Hard to Develop Vaccines
Prof Roman Prymula, Professor Preventive Medicine, Charles University in PragueCzech Republic
Oct 2915:30
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Intranasal adjuvanted vaccines – Inducing mucosal immunity

New Vaccine Technology
Oct 2915:45
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Influenza vaccines immunological assessment

Respiratory Vaccines
Reserved for Prof Emanuele Montomolim Chief Scientific Officer, VisMederi Srl & Full Prof. of Public Health, University of Siena

Oct 2915:45
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The rationale of combining biomarkers and checkpoint inhibitors with vaccines

Immuno-Oncology Profiling
Oct 2915:45
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A new strategy: Latest progress on a Herpes Zoster Vaccine

New Vaccine Technology
Oct 2916:00
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Efficacy, safety and immunogenicity of a plant-derived quadrivalent Virus-Like Particles influenza vaccine in adults

Respiratory Vaccines
Oct 2916:00
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Updates on oral vaccination strategies to protect against rabies

Veterinary Vaccines
Dr Tony Fooks, Head of Wildlife Zoonoses and Vector-Borne Diseases Research Group, Animal Health and Veterinary Laboratories AgencyUnited Kingdom
Oct 2916:00
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Synthetic vaccines to facilitate a rapid response to newly emerging infectious diseases

New Vaccine Technology
Oct 2916:15
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Glioblastoma Immunotherapy (VBI-1901) cancer vaccine update

Immuno-Oncology Profiling
Oct 2916:15
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A single-dose live-attenuated Zika vaccine

Hard to Develop Vaccines
Oct 2916:15
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Using mRNA technology from universal flu to malaria vaccines

New Vaccine Technology
Oct 2917:00
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RSV sessions on Ph2 RSV CODP formulations

Respiratory Vaccines
Oct 2917:00
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Optimising combination therapies with the aim to enhance immune and clinical responses

Immuno-Oncology Profiling
Dr Daniel Speiser, Head of Clinical Tumour Biology and Immunotherapy Group, University of LausanneSwitzerland
Oct 2917:00
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Incentivizing industry to develop vaccines for neglected diseases in LMIC

Veterinary Vaccines
Dr Jeremy Salt, Chief Scientific Officer, GalvmedUnited Kingdom
Oct 2917:00
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Adjuvanted vaccines can help protect immunocompromised individuals, taking the example of Shingrix

Hard to Develop Vaccines
Eduardo de Gomensoro, Director, Global Medical Affairs Lead, Zoster, GSKUnited States
Oct 2917:15
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Next generation(s) of synthetic glycoconjugate vaccines

New Vaccine Technology
Oct 2917:30
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A novel allergen-encoding immunotherapeutic vaccine in the treatment of peanut allergy

Immuno-Oncology Profiling
Professor John Hayball, Professor, University of South AustraliaAustralia
Oct 2917:30
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Controlling zoonotic diseases in the developing world

Veterinary Vaccines
Oct 2917:30
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CEPI supported vaccine development on Lassa Fever and MERS vaccine development

New Vaccine Technology
Oct 2917:45
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A renewed interest in developing EBV vaccine

Hard to Develop Vaccines
Dr Jeffrey Cohen, Chief of Laboratory of Infectious Diseases, NIHUnited States
Oct 2917:45
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CEPI supported vaccine development on Lassa Fever and MERS vaccine development using a DNA platform

New Vaccine Technology
Joseph Kim, Chief Executive Officer, Inovio PharmaceuticalsUnited States

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Oct 3008:30
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Oct 3008:35
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Keynote: The role of vaccines, public awareness and industry in preventing further AMR

Keynotes
  • How critical is the risk?
  • Vaccines can’t do it alone – How can we reduce the development of drug resistance?
  • Increasing investment in R&D that meets global public health needs
  • The need for a holistic and collaborative strategy including cross species considerations
Oct 3010:00
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Chair’s opening remarks

Veterinary Vaccines
Oct 3010:00
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Chair’s opening remarks

Bioprocess, Delivery & Manufacture
Oct 3010:05
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Moving from pre-clinical to clinical

Clinical Development
Senior representative, Viroclinics
Oct 3010:05
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How do we overcome CAR T immunotherapy limitations to enable the treatment of more patients?

Immuno-Oncology Profiling
Oct 3010:05
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Spy and Snoop technologies to accelerate vaccine development

Veterinary Vaccines
- SpyTag, SnoopTag and DogTag are superglues for unbreakable peptide-mediated nano-assembly.
- SpyCatcher-linked virus-like particles enable Plug-and-Display vaccine assembly.
- Spy-VLPs induce potent antibody responses with potential against challenging human and veterinary targets, including malaria, bacteria and viral pathogens.
- Modular vaccine assembly has potential for personalised medicine (e.g. for cancer) and also to accelerate response to outbreaks
Oct 3010:05
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What can we do to manage AMR? MRSA, C.diff and E.coli control efforts including Abx practices

Anti-Microbial Resistance
Professor Mark Wilcox, Professor of Medical Microbiology & Deputy-Chair, APRHAI, University of LeedsUnited Kingdom
Oct 3010:05
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Bridging the Global Health Gap – Viral and bacterial vaccine development at Intravacc

Bioprocess, Delivery & Manufacture
Oct 3010:20
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Latest advancements in production process intensification to support demand for affordable vaccines

Bioprocess, Delivery & Manufacture
Senior representative, Batavia Biosciences
Oct 3010:35
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Early and late phase clinical trial design conundrums Use of surrogate endpoints, differential efficacy / safety in diverse populations, accurate measures of exposure

Clinical Development
Senior representative, PRA Health Sciences
Oct 3010:35
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Combining Innate and Adaptive Immunity: NK Receptors for CAR T Cell Therapy

Immuno-Oncology Profiling
Oct 3010:35
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Developing vaccines with superior stability

Veterinary Vaccines
  • Why do we need vaccines with improved stability?
  • Use outside the cold chain improves immunisation coverage
  • Is there enough innovation in formulation of vaccines?
  • Conventional approaches to vaccine formulation
  • Innovative formulations to achieve superior vaccine stability
Oct 3010:35
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Bad bugs overview, what are the AMR transmission patterns?

Anti-Microbial Resistance
Dr Trevor Lawley, Group Leader, Wellcome Trust Sanger Institute Genome Research LtdUnited Kingdom
Oct 3010:35
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High-density vero cell perfusion culture in packed-bed bioreactors

Bioprocess, Delivery & Manufacture
Dr Joerg (Jörg) Schwinde, Eppendorf Inc.Malaysia
Oct 3012:05
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Challenges of assay validation including cell-based format

Clinical Development
Dr Bassam Hallis, Head of Pre Clinical Development and General Project Manager, Public Health EnglandUnited Kingdom
Oct 3012:05
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Using baculovirus vector technologies for vaccine production

Veterinary Vaccines
  • Increasing vaccine potency and facilitating broad immune responses
Oct 3012:05
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Why and how the Netherlands maintain one of the lowest AMR rates? What bugs can be stopped by vaccines and which likely are more difficult

Anti-Microbial Resistance
Prof Marc Bonten, Professor, UMC UtrechtNetherlands
Oct 3012:20
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DiViNe project - Affinity chromatography for vaccines purification

Bioprocess, Delivery & Manufacture
Senior representative, Affilogic
Oct 3012:35
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Adjuvants: Their optimal delivery and how they advance into clinical evaluation and assessment of their performance

Clinical Development

Oct 3012:35
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Priming tumours for immune checkpoint blockade using oncolytic viruses

Immuno-Oncology Profiling
Dr Adel Samson, Lead, Translational Cancer Immunotherapy Group, University of LeedsUnited Kingdom
Oct 3012:35
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The regulation of veterinary vaccine development

Veterinary Vaccines
Dr Mel Munro, Project Manager, Biologicals Regulatory Affairs, Triveritas LimitedUnited Kingdom
Oct 3012:35
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Phasing out broad spectrum antimicrobial use: issues, challenges and potential paths forward?

Anti-Microbial Resistance
The current unnecessary use of broad-spectrum antibiotics results in both microbiome dysbiosis-related health issues and the emergence and spread of antibiotic-resistance traits – and therein set-up the anticipated role of pathogen-targeted antibiotics and antibacterial vaccines in limiting the future emergence and spread of AMR
Dr (Anthony) Simon Lynch, Senior Scientific Director - Microbiology, Infectious Diseases & Vaccines Therapeutic Area, Janssen R&DNetherlands
Oct 3012:35
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Virus safety for viral vaccines and viral vectors

Bioprocess, Delivery & Manufacture
Oct 3012:50
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Large animal vaccine challenge models and recombinant vaccine technology

Veterinary Vaccines
Oct 3013:05
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Clinical development of emerging pathogen vaccines using adenoviral vector platform technology

Clinical Development
Oct 3013:05
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Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity

Immuno-Oncology Profiling
Dr Peter Timmerman, Chief Scientific Officer, Pepscan TherapeuticsNetherlands
Oct 3013:05
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Yeast-based subunit marker vaccines go multivalent

Veterinary Vaccines
Oct 3013:05
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Development of a new manufacturing platform technology for human vaccines

Bioprocess, Delivery & Manufacture
Creating scale-down models that can be accurately applied to the commercial scale
Oct 3015:05
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Unplanned parainfluenza virus infection on an isolation ward – A case study

Clinical Development
Title subject to change
Dr Adrian Wildfire, Project Director - Infectious Diseases & Viral Infection Unit, SGS Life Science ServicesSwitzerland
Oct 3015:05
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Hope for late-stage ovarian cancer: Development of a personalized dendritic cell vaccine

Immuno-Oncology Profiling
  • Improving dendritic cell platforms
  • Initiating large scale trials and combination therapies
Oct 3015:05
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Novel RNA particle vaccine platform for animal health applications

Veterinary Vaccines
Oct 3015:05
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Reduction of otitis by pneumococcal conjugates

Anti-Microbial Resistance
Oct 3015:05
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A proven single-use platform to accelerate the development and production of viral vaccines

Bioprocess, Delivery & Manufacture
Oct 3015:35
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Identifying knowledge gaps and combinational approaches to gain an effective model for Pertussis

Clinical Development
Dr Dimitri Diavatopoulos, Department of Pediatrics/ Laboratory of Pediatric Infectious Diseases (LPID), Radboud University Medical CenterNetherlands
Oct 3015:35
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Synergy of DNA Vaccines with checkpoint inhibitors and Standard of Care Agents for Prostate Cancer

Immuno-Oncology Profiling
  • Selection of appropriate vaccine antigens for prostate cancer
  • Updates from ongoing translational trials of DNA vaccines in prostate cancer with anti-PD-1
  • DNA vaccines to augment androgen deprivation therapy
Oct 3015:35
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Innovation milestones in Aqua Health; DNA vaccines

Veterinary Vaccines
  • What is a DNA vaccine, and how do they work?
  • What does it take to bring a new technology into the EU; what hurdles do you face as you prove a new technology is safe and effective?
Oct 3015:35
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TB, A global problem: One of the biggest bacterial disease burden

Anti-Microbial Resistance
Prof Mark Hatherill, Professor, S.A. Tuberculosis Vaccine InitiativeSouth Africa
Oct 3015:35
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Platform manufacturing processes - Designing vaccines for the Global Health need?

Bioprocess, Delivery & Manufacture
Oct 3016:05
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A human challenge model of Bordetella pertussis infection, for the testing of novel whooping cough vaccines

Clinical Development
Oct 3016:05
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Targeting IDO positive cells with IO102, an immune modulating vaccine

Immuno-Oncology Profiling
Oct 3016:05
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The importance of transboundary and emerging infectious diseases

Veterinary Vaccines
Oct 3016:05
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Antibody–Antibiotic Conjugates: A Novel Therapeutic Platform against Bacterial Infections

Anti-Microbial Resistance
Oct 3016:05
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Targeted delivery in rational vaccine design

Bioprocess, Delivery & Manufacture
How physico-chemical properties of liposomes, emulsions, antigens and different routes of delivery can influence the immunological outcome
Oct 3016:35
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World Bank collaboration and its capacity for vaccine trials in emerging countries (strategy and plans)

Clinical Development
Oct 3016:35
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Improving cancer vaccine manufacturing to GMP compatible bioprocesses

Immuno-Oncology Profiling
Oct 3016:35
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Plasmid launched live attenuated virus vaccines for endemic and epizootic viral livestock diseases

Veterinary Vaccines
Dr Joeri Auwerx, Director, Discovery Research, ViroVet N.V.Belgium
Oct 3016:35
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Oct 3016:35
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Advances in intradermal drug delivery

Bioprocess, Delivery & Manufacture
Glen Zimmermann, Senior Director Business Development, West Pharmaceutical ServicesIsrael
Oct 3017:05
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Challenges in Phase IV studies and register based impact research

Clinical Development
Professor Hanna Nohynek, Deputy Director, National Institute for Health and WelfareFinland
Oct 3017:05
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The future of veterinary vaccine delivery and rethinking vaccination strategies

Veterinary Vaccines
Oct 3017:05
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Create your personal agenda –check the favourite icon

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A Case for a (new) Vaccine

A Case for a Vaccine
Where alternative treatments are used, is there a case for a vaccine against the following diseases?
Oct 3109:10
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Pre-clinical vaccination success towards the challenge of eliciting HIV envelope glycoprotein-directed broadly neutralizing antibodies (bNAbs)

A Case for a Vaccine
Oct 3109:10
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Beyond PD-1/PD-L1: New Horizons and Roadblocks in Cancer Immunotherapy

Immuno-Oncology Profiling
Dr Laszlo Radvanyi, Senior Vice President, Senior Scientific Advisor, EMD SeronoUnited States
Oct 3109:10
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Looking beyond antibiotics: Time to vaccinate

Veterinary Vaccines
  • How do we encourage increased vaccine usage?
  • Establishing good vaccine practice and compliance
Oct 3109:10
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Influenza A and B – Rapid and Precise Antibody-Based Quantification using Sartorius’ Virus Counter 3100

Bioprocess, Delivery & Manufacture
Oct 3109:40
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TB vaccine development efforts

A Case for a Vaccine
Professor Helen Mcshane, Professor Of Vaccinology Wellcome Senior Fellow PI Head Of TB Vaccines Group, The Jenner Institute - University of OxfordUnited Kingdom
Oct 3109:40
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How do we maximise the therapeutic potential of Immuno-oncology through novel combinations?

Immuno-Oncology Profiling
Dr Maria Karasarides, Executive Director, ImmunoOncology, Regeneron PharmaceuticalsUnited States
Oct 3109:40
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Overcoming the factors hindering the usefulness of veterinary vaccines as alternatives to antibiotics

Veterinary Vaccines
  • Veterinary vaccines can reduce the need for antibiotics, but what factors are currently limiting their usefulness for this?
  • An overview of veterinary vaccinesas antibiotic alternatives today and tomorrow
Oct 3109:40
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Interactive panel: External collaborative research and partnering opportunities for vaccine development

Vaccine Partnerships
Panellists to be announced
Oct 3109:40
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The plant-based Proficia™ technology: a game changer for influenza vaccine production

Bioprocess, Delivery & Manufacture
Senior representative, Medicago
Oct 3110:10
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How can we create a more effective pertussis vaccine?

A Case for a Vaccine
Oct 3110:10
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Continuous production of influenza viruses in cell culture and use of continuous downstream processing for purification of virus particles/viral antigens

Bioprocess, Delivery & Manufacture
Reserved for IFPMA
Oct 3111:20
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Strategies for global hepatitis C elimination – Do we need a prophylactic vaccine?

A Case for a Vaccine
Dr Michael Manns, Professor, Hannover Medical SchoolGermany
Oct 3111:20
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Antibody based combination immunotherapy

Immuno-Oncology Profiling
Oct 3111:50
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Fast authorizations of vaccines for emerging diseases

Veterinary Vaccines
Dr Rosario Bullido, Head of Veterinary Inmunological Medicines Assessment Unit Veterinary Medicines Department, AempsSpain
Oct 3111:50
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Panel: Insights on how to implement new business partnership models for international collaboration among vaccine manufacturers and government ministries

Vaccine Partnerships
Speakers to be announced shortly
Oct 3111:50
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Bioprocess engineering of insect cells for enhanced production of VLPs for vaccine development

Bioprocess, Delivery & Manufacture
Oct 3112:20
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GAS vaccine efforts

A Case for a Vaccine
Prof Anne Botteaux, Molecular Bacteriology Laboratory, Universite Libre De BruxellesBelgium
Oct 3112:20
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Unbiased functional screening of large bispecific antibody panels to unlock novel biology

Immuno-Oncology Profiling
Oct 3112:20
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From development to commercialization of vaccines – A case study

Bioprocess, Delivery & Manufacture
Oct 3114:00
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Status of vaccine confidence around the world

Keynotes
  • Social and political factors that can affect uptake of vaccines
  • How can we better educate the public the benefits of immunisation?
  • How can public health institutions, government and vaccine developers help with building a coherent story
  • AEFI surveillance and risk communication
  • Are we overlooking the power of social media?
Professor Hanna Nohynek, Deputy Director, National Institute for Health and WelfareFinland
Fred Zepp, Medical Director and Chairman of the Department of Paediatrics, University Medicine MainzGermany
Prof Roman Prymula, Professor Preventive Medicine, Charles University in PragueCzech Republic
Oct 3114:50
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Flumist vaccine effectiveness – It’s return and the real story

Keynotes
  • Questions over the effectiveness of the live attenuated vaccine
  • Why it lost its recommendation
  • The journey, investigation and trial data to rectify this
Dr Helen Bright, Head, Team of Cell and Molecular Biologics, MedImmuneUnited Kingdom
Oct 3115:15
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Closing plenary: The future of vaccinology: Incorporating bioinformatics, omics and structural vaccinology into vaccine design

Keynotes
  • A bottleneck for all, the ability to manage and analyze in an integrative with all the data that is generated
  • interpreting everything into something meaningful
last published: 19/Jun/18 15:15 GMT

 

 

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