My research, funded by UK Medical Research Council fellowships (Career Development Award: 2019 – 2024; and Senior Fellowship: 2024 - 2029) and US National Institute of Health grants, focuses on next-generation vaccines against major bacterial pathogens. Using the chief causes of bacterial meningitis as exemplar, my lab is currently employing innovative use of Reverse Vaccinology 2.0, and bacterial and synthetic cell glycoengineering to the development of a next-generation, combined meningococcal-pneumococcal glycoconjugate vaccine. Efforts in my lab are also geared towards understanding the human adaptive immunity to, and prevention of disease due to, AMR pathogens of concern, N. gonorrhoeae and Klebsiella pneumoniae.