MI LIU | Professor
Soochow University

Name: Liu Mi Title and position: Distinguished Professor, Institute: Department of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University CSO,  Beijing Darwin Biotech Co., LTD   Email: mi.liu@suda.edu.cn   Research Areas: (1) New drugs based on proteins derived from stem cells to treat neurodegenerative diseases (2) Preventive and therapeutic cancer vaccines (3) Novel T cell therapy (4) Novel detection technology of tumor antigen-specific T cells   Research Experience: The studies are practical and have close cooperation with pharmaceutical enterprises. Several projects have successfully transferred to pharmaceutical companies. As the first inventor, he has applied for more than 70 international invention patents and Chinese invention patents, among which more than 20 have been authorized. Some international invention patents have entered the United States, the European Union, Japan, Canada, South Korea, Australia, Brazil, etc. Work Experience 2018.12- Current   Professor  Soochow University 2014.11-2018.11   Postdoc   Harvard Medical School Education 2011.01–2014.08 PhD Drug Formulation and Delivery, Swiss Federal Institute of Technology Zürich (ETH Zürich)   Representative published papers:

1. Weibiao Zeng#, Jin Wang#, Zhike Chen#, Jian Yang#, Ao Zhu, Yan Zheng, Xianlan Chen, Yuhan Liu, Leilei Wu, Yufeng Xie, Sheng Ju, Jun Chen, Cheng Ding, Chang Li, Xin Tong*, Mi Liu*, Jun Zhao*, Efficient predictor for immunotherapy efficacy: detecting pan-clones effector tumor antigen specific T cells in blood by nanoparticles loading whole tumor antigens, Advanced Science, 2024, Nov 5:e2409913,https://doi.org/10.1002/advs.202409913.
2. Jin Wang#, Weibiao Zeng#, Jiao Xue#, Ao Zhu, Xianlan Chen1,4, Yan Zheng1,4, Yuhan Liu, Songbing Qin*, Jun Zhao*, Mi Liu*, Efficient biomarker for immunotherapy: measuring broad clones effector tumor antigen specific T cells in blood of esophageal cancer patients, Analytical Chemistry, 2024, DOI:10.1021/acs.analchem.4c04049.
3.  Li, Baisong; Ma, Lin; Li, Xiwen; Suleman, Zainab; Liu, Changming; Piskareva, Olga*; Liu, Mi*, Size matters: altering antigen specific immune tolerance by tuning size of particles, Journal of Controlled Release, 2024, 373, 823-836.
4. Lu Diao, Mi Liu*, Rethinking Antigen Source: Cancer Vaccines Based on Whole Tumor Cell/tissue Lysate or Whole Tumor Cell, Advanced Science, 2023, https://doi.org/10.1002/advs.202300121.
5. Xiangxiang Xu#, Meng Zhang#, Xiaoyan Liu,1 Mingze Chai, Lu Diao, Lin Ma, Shuang Nie, Minghao Xu, Yipeng Wang, Fengfeng Mo*, and Mi Liu*, Probiotics formulation and cancer nanovaccines show synergistic effect in immunotherapy and prevention of colon cancer, iScience, 2023, 26, 107167.
6. Jianting Ma, Zuofu Peng, Lin Ma, Lu Diao, Xinyu Shao, Zhiming Zhao, Lele Liu, Liang Zhang, Chenrong Huang, and Mi Liu*，A Multiple-Target Simultaneous Detection Method for Immunosorbent Assay and Immunospot Assay, Analytical Chemistry, 2022, 94, 8704−8714.
7. Lin Ma, Lu Diao, Zuofu Peng, Yun Jia, Huimin Xie, Baisong Li, Jianting Ma, Meng Zhang, Lifang Cheng, Dawei Ding, Xuenong Zhang, Huabing Chen, Fengfeng Mo, Honglv Jiang, Guoqiang Xu, Fenghua Meng, Zhiyuan Zhong, Mi Liu*, Immunotherapy and prevention of cancer by nanovaccines loaded with whole-cell components of tumour tissues or cells, Advanced Materials, 2021, 43, 2104849.
8. Mi Liu, Jean-Christophe Leroux, Marc Andre Gauthier, Conformation-function relationships for the comb-shaped polymer pOEGMA, Progress in Polymer Science, 2015, 48, 111–121.
9. Mi Liu, Pål Johansen, Jean-Christophe Leroux, and Marc Andre Gauthier, Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo, Nature Communications, 2014, 05, 5526.
10. Mi Liu, Pasquale Tirino, Milos Radivojevic, Daniel J. Phillips, Matthew I. Gibson, Jean-Christophe Leroux, Marc Andre Gauthier, Molecular sieving on the surface of a protein provides protection without loss of activity. Advanced Functional Materials, 2013, 23, 2007–2015.

  Representative honors Mary K. Iacocca Genetics/Immunology Fellowship,   07.2017-07.2018, Harvard Medical School Mary K. Iacocca Fellowship, 07.2015-07.2016, Harvard Medical School