Dr. Elizabeth Norton, MPH, PhD: Dr. Norton is an Assistant Professor (tenure-track) at Tulane School of Medicine Department of Microbiology & Immunology. A major portion of her laboratory investigates LT-based adjuvants and proteins and mechanisms of vaccine efficacy related to age or disease status. She began her training at the CDC in Atlanta, GA, which included cellular immunologic assays on human samples and identifying correlates of sepsis in children. In her doctoral research at Tulane University, she evaluated how modulation of innate immunity can protect subsequent Influenza infection. In Dr. Norton’s post-doctoral research, she performed direct characterization of dmLT adjuvant properties, focusing on mechanisms of enhanced mucosal and systemic immunity. She has served as a Co-Investigator and project manager in dmLT adjuvanted vaccine studies including Gates Foundation funded polio research and NIH-funded tuberculosis and shigella research in mice and nonhuman primate models. Her lab currently also performs stability testing on dmLT GMP material, novel formulation evaluations, and mechanistic studies. In addition, Dr. Norton has pioneered novel LTA1 adjuvant for intranasal use, with relevant studies on LTA1 efficacy and safety in mouse immunization and infection models, including ETEC and influenza and for multidrug resistant Klebsiella pneumoniae.
Advanced vaccine delivery methods: novel routes and technologies to optimize administration, efficacy, and accessibility.
2pm Chair’s Opening Remarks: Vaccine Delivery Landscape Overview
2:15pm -4:00pm Vaccine delivery presentations:
4:00 Panel: Targeting Mucosal Surfaces in Respiratory Vaccine Development