Casey McPherson is an accomplished drug developer, entrepreneur and singer-songwriter based in Austin, Texas. Known for his two #10 US hits, he shifted his focus to rare disease commercial development after his daughter Rose was diagnosed with a rare genetic condition. In 2020, he founded the To Cure A Rose Foundation and later founded RareLabs, a lab dedicated to developing pre-clinical treatments for rare diseases with 20 programs in the pipeline, and 8 new treatments discovered. In 2023, he launched AlphaRose Therapeutics, a platform to commercialize rare genetic disease therapeutics at scale. Casey continues to build solutions for precision medicine while enjoying life with his two daughters.
Orphan disease drug development and commercialization is often fragmented - with an inefficient clinical development model, an incorrect way of measuring Return of Investment and a commercial model that is often unattractive vis-a-vis other disease states. Imagine an approach where there is access to knowledge, infrastructure and mission-dedicated evergreen capital to systematically develop new medicines for orphan diseases. Imagine an investment vehicle with dual objectives: Return on mission- curing rare diseases and Return on capital: Making money while doing that! In this panel, we will discuss both the operational and capitalization novelties in this new model. Capital allocations from foundations and family offices / UHNWIs can enable such a construct, along with an infrastructure support system from hospitals, scientists, drug manufacturers.