Varient is a scalable digital health platform to create touch points with, and collect real-world evidence from, patients living with genetic and rare disease. Varient creates a win-win scenario for all stakeholders: the patients receive off-label treatment decision support for their symptoms, academics can conduct natural history and genotype-phenotype studies, and pharma gains access to the data and clinical operations tool that they needed to efficiently create new orphan therapies - which the patients so desperately need.