Michael Nagler, MD, PhD, is Deputy Director of the Center for Laboratory Medicine at Inselspital, Bern University Hospital, and Associate Professor at the University of Bern. As a hematologist, epidemiologist, and laboratory medicine specialist, he combines clinical expertise with a strong focus on diagnostic research and innovation. In his leadership role, he drives digital transformation and automation initiatives while promoting modern, interdisciplinary approaches to healthcare organization and leadership. His research focuses on the development, validation, and implementation of innovative diagnostic tools, with a particular emphasis on machine learning–based decision support.
Diagnostic innovation, from advanced analytical techniques to machine learning, is transforming medicine. Yet most innovations never reach patients. Why? Because we focus on technologies, not on clinical use. In practice, value is created when a tool improves a specific decision, at a specific moment, for a specific patient. Our work shows that successful translation requires more than innovation: it starts with a clear clinical need, uses real-world data, follows phased validation, and integrates seamlessly into clinical workflows. If we get this right, we can turn promising ideas into trusted diagnostic tools that truly improve care and outcomes.
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