Madeline Díaz-Serrano | Sr. Scientist, Chemistry
Merck

Madeline is an accomplished Senior Scientist with expertise in chemical analysis of pharmaceutical small molecules and biophysical characterization of large molecules. She has demonstrated exceptional leadership in guiding teams through early-phase development and commercialization processes. As a Senior Technical Leader at Merck, she has overseen drug product testing, stability studies, analytical method development and validation, specification setup, filing support and leading safety and automation initiatives. Her pioneering research in graphene nanoelectronics and postdoctoral work on graphene field-effect transistors for biomarker detection have been widely recognized through numerous presentations and scientific publications. Madeline holds a Doctoral degree in Analytical Chemistry from University of Puerto Rico, complemented by certification in Biotechnology Science and a Bachelor's degree in Chemistry.

Appearances:

Day 2: 16th October @ 14:40

Automation on analytical laboratory for finished product dosage forms

The pharmaceutical industry has long aimed to fully automate analytical laboratories, from sample preparation to final data reporting. Automation enables continuous sample processing, manages complex testing procedure, increases precision and data quality, ensures traceable audit trails for compliance, eases lab transfers, reduces errors and costs, and enhances safety. Many companies now use automated platforms for tasks like dissolution, content uniformity and assay/degradation across various dosage forms. This study is expected to encourage a wider application of the very advanced automated system usage in routine pharmaceutical analysis as dissolution and assay/degrades, and support stability studies in late phase product development and commercial phase.

Madeline Díaz-Serrano, Sr. Scientist, Chemistry, Merck

Hardikkumar Ghelani, Sr. Scientist, Merck