Joann Diray Arce | Assistant Professor of Pediatrics
Harvard Medical School

Dr. Joann Diray Arce is an Assistant Professor of Pediatrics at Harvard Medical School and Affiliate Faculty at the Broad Institute of MIT and Harvard. She serves as Lead of the Data Management and Analysis Core (DMAC) within the Precision Vaccines Program at Boston Children’s Hospital, where she directs large-scale systems immunology and multi-omics research initiatives. Dr. Arce is a systems immunologist with expertise in genomics, transcriptomics, proteomics, metabolomics, and integrative computational modeling. Her work focuses on defining cellular and molecular signatures that predict vaccine immunogenicity, durability, safety, and immune development across the lifespan, with particular emphasis on early life. She leads multi-institutional and international collaborations supported by NIH and global partners, integrating high-dimensional immune profiling with advanced machine learning approaches to identify predictive immune endotypes.