Heath Damron is Director of the Vaccine Development Center (VDC) at West Virginia University and Co-founder and Chief Scientific Officer of Montani Biotechnologies, Inc. He works in pre-clinical vaccine development, and the VDC collaborates with industry to evaluate experimental vaccines, including programs for pertussis, COVID-19, Lyme disease, AMR pathogens, and others. Over the past seven years, his research has centered on new applications of mRNA technology. At Montani, he helps shape scientific strategy and partnerships focused on developing mRNA genetic adjuvants to support personalized neoantigen cancer therapies and other next-generation vaccines. At the World Vaccine Congress Washington 2026, he will share ongoing R&D efforts in emerging mRNA approaches.
Introduction & Context:o Challenges with mRNA vaccine durability and breadth o Emerging role of genetic adjuvants o Relevance to pandemic preparedness and immunological innovationTalk 1: Mechanisms & Promise of Genetic Adjuvantso Overview of cytokine-encoded mRNA adjuvants o IL-12 and other promising candidates o Immunological mechanisms and delivery challengesTalk 2: Enhancing mRNA Vaccine Breadth & Durabilityo Case studies on combining mRNA vaccines with genetic adjuvants o Data on durability, breadth, and safety o NIH funding landscape and regulatory considerationsTalk 3: Translational & Clinical Perspectiveso Preclinical and early clinical data o Formulation and delivery innovations o Potential applications beyond infectious disease (e.g. allergy, autoimmunity)Discussion & Audience Q&Ao Where do genetic adjuvants fit in the current vaccine tech landscape? o Regulatory hurdles and funding gaps o Opportunities for collaboration and future research