James D Chambers, PhD, is an investigator at the Center for the Evaluation of Value and Risk in Health at Tufts Medical Center and a Professor of Medicine at Tufts University School of Medicine. He developed the SPEC Database, a novel resource of specialty drug coverage policies issued by major U.S. commercial health plans, which serves as the foundation for much of his research. His work uses mixed methods to examine health plan decision-making, highlighting variation in patients’ access to specialty therapies across commercial plans and in the use of utilization management tools. He has also assessed the factors influencing coverage decisions, finding that a drug’s cost-effectiveness is associated with the restrictiveness of plan policies. He also developed a database of the added health gains and costs of new drugs compared to existing treatments, which he has used to evaluate the relative value of specialty vs non-specialty drugs, drugs for rare disease vs drugs for more prevalent conditions, and small molecule vs. biologics. James earned his MPharm from Queen’s University Belfast and worked as a pharmacist in the UK and Ireland before completing an MSc at the University of York and a PhD in Health Economics at Brunel University.