Salah Mansour | Associate Professor, iNKT Cell Therapy
University of Southampton

Dr Salah Mansour is a senior immunologist at the University of Southampton, specialising in unconventional T cell biology and its application to advanced immunotherapies. His research focuses on invariant natural killer T (iNKT) cells, CD1-restricted T cells, and their therapeutic potential in cancer and infectious diseases. Dr Mansour leads efforts to understand and harness functionally distinct iNKT subpopulations for next-generation cell therapies, particularly in haematological malignancies such as acute myeloid leukaemia (AML). He directs a multidisciplinary programme integrating translational immunology, single-cell multiomics, and cellular engineering, and has established strategic collaborations with biotech partners. His work is supported by Cancer Research UK, the UK Health Security Agency (UKHSA), and the Medical Research Council, and he contributes actively to clinical translation within the Southampton Centre for Cancer Immunology. Dr Mansour is also at the forefront of research into CD1 antigen presentation pathways and their role in shaping anti-tumour immunity. His goal is to develop scalable, off-the-shelf cellular therapies informed by deep mechanistic insight and patient-centred translational science.