Paul Gissen is the Head of the Genetics and Genomic Medicine Department at the UCL Great Ormond Street Institute of Child Health, London, UK, Honorary Consultant in paediatric metabolic diseases at Great Ormond Street Hospital for Children NHS Foundation Trust, Deputy Lead for Novel Therapies theme in GOSH NIHR Biomedical Research Centre.

Professor Gissen obtained his medical degree from the University of Glasgow, UK, in 1995, before completing his Paediatrics and sub-specialty in Inherited Metabolic Disorders training at Manchester, Sheffield and Birmingham Children’s Hospitals (all within the UK). Professor Gissen completed his PhD at Birmingham University, where he investigated the genetics of rare paediatric liver disorders.

Paul’s clinical interests lie with intracellular trafficking disorders such as arthrogryposis, renal dysfunction, cholestasis syndrome (ARC), Niemann-Pick disease type C (NPC) and Neuronal Ceroid Lipofuscinosis. His research achievements so far include the identification of more than 20 novel disease genes mutations which are responsible for inherited paediatric disorders and uncovering the underlying molecular pathology in ARC syndrome. Professor Gissen’s research group is actively involved in translating novel therapies into clinical practice from laboratory research to clinical trials.