Sebastian is leading the protein engineering division at Ichnos Glenmark Innovation (IGI) in Lausanne. Before, he worked on implementing the yeast display technology at Pieris Pharmaceuticals and developing a T-cell engager platform at Molecular Partners. He performed his post-doctoral research at Dartmouth (NH), holds a PhD in Molecular Biotechnology from the Royal Institute of Technology (KTH) in Stockholm and studied at University of Heidelberg and Technical University of Munich.
IGI’s BEAT platform (Bispecific Engagement by Antibodies based on the TCR) facilitates the design of multi-specific antibodies using efficient heavy-chain heterodimerization and diverse, developable Fabs incorporating a common light chain (cLC). The discovery process from phage display to final format as well as case studies will be presented.