Agenda

Basel, 30 September 2025 - 2 October 2025

Schedule

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Sep 309:05
Conference pass

Chair's opening remarks

Keynotes
antibodies
immunotherapy
biosimilars
manufacturing & bioprocessing
clinical trials
Sep 309:10
Conference pass

Achieving Sustainability in the Biologics Market

Keynotes
antibodies
immunotherapy
biosimilars
manufacturing & bioprocessing
clinical trials
barry chester, director, pfizer
Sep 309:35
Conference pass

Accelerate ADC Development from DNA to BLA Through fully Integrated CMC and manufacturing platforms

Keynotes
antibodies
immunotherapy
biosimilars
manufacturing & bioprocessing
clinical trials

Senior Representative, WuXi XDC

Sep 3010:00
Conference pass

The Digital Advantage

Keynotes
antibodies
immunotherapy
biosimilars
manufacturing & bioprocessing
clinical trials

Senior Representative, Danaher

Sep 3011:30
Conference pass

Antibody-based product successes and progresses in 2024

Keynotes
antibodies
Sep 3011:30
Conference pass

Biosimilars Late Stage Development: Back to the Future

Keynotes
biosimilars
late stage development
Uwe Gudat, Chief Medical Officer, Biocon Biologics
Sep 3011:30
Conference pass

Bringing Medicine Development to patients, the why and the how

Keynotes
clinical trials
Sep 3011:30
Conference pass

Developments at AIVITA Biomedical

Keynotes
immunotherapy
Sep 3011:30
Conference pass

Systems biology approaches in improving quality and titer of biologics

Bioprocessing: Upstream & Downstream
manufacturing & bioprocessing
Sep 3011:30
Conference pass
Sep 3011:50
Conference pass

Accelerated and Robust Cell Line Development in HEK293 Cells for Increased Protein Yields and Improved Protein Quality

Bioprocessing: Upstream & Downstream
manufacturing & bioprocessing

Senior Representative, ExcellGene

Sep 3011:55
Conference pass

From Apollo™X cell line to 20K L Bioreactor: partnering manufacturing strategies and facility design for patient-centric medicine delivery

Keynotes
antibodies

Senior Representative, FUJIFILM Diosynth

Sep 3012:10
Conference pass

Genetic engineering strategies to eliminate lactate production and control ammonia secretion

Bioprocessing: Upstream & Downstream
manufacturing & bioprocessing
Sep 3012:20
Conference pass

Biomarkers in clinical trials and clinical practice – why one biomarker is usually not enough

Keynotes
immunotherapy
Thomas Hach, GPCH, Novartis
Sep 3012:20
Conference pass

Biosimilars Keynote Panel

Keynotes
biosimilars
late stage development
Haoheng (Sandy) Yan, Head of US Regulatory Affairs, Shanghai Henlius Biotech Co., Ltd.
Sep 3012:20
Conference pass

Keynote Panel Discussion: Accelerate ADC and bioconjugates development - sponsored by WuXi XDC

Keynotes
antibodies

Panellists TBA

Sep 3012:30
Conference pass

Introducing Super Refined™ Poloxamer 188: optimised for mammalian cell culture with exceptional batch-to-batch consistency

Bioprocessing: Upstream & Downstream
antibodies

Senior Representative, Croda Pharma

Sep 3013:10
Conference pass

Automated bioinformatics pipelines for rapid in silico analysis – In silico antibody assessment selection

Showcase
showcase

Senior Representative, PipeBio, a Benchling Company

Sep 3013:30
Conference pass

The critical role of the 5,000 L bioreactor: Bridging drug substance supply needs between early and late-stage development

Showcase
showcase

Senior Representative, Thermo Fisher Scientific

Sep 3013:50
Conference pass

Title TBA

Showcase
showcase

Senior Representative, Seromyx

Sep 3014:20
Conference pass

BiXAb MAIT engagers: redirecting an abundant cytotoxic T-cell subset to control solid tumors.

Bispecifics & Multispecifics
Simon Plyte, CSO, Biomunex Pharmaceuticals
Sep 3014:20
Conference pass

BPT567 (PD1-IL18) induces potent anti-tumor immune responses by targeting IL-18BP-resistant IL-18 to PD-1+ T cells in the tumor microenvironment

Armed Antibodies
antibodies
Sep 3014:20
Conference pass

Developability and risk-based control strategies of antibodies and ADCs

CMC & Developability
antibodies
Sep 3014:20
Conference pass

Developability and risk-based control strategies of antibodies and ADCs

CMC & Developability
antibodies
Sep 3014:20
Conference pass

Discovery, development and manufacturing of optimized biologics using engineered CHO cells.

Bioprocessing: Upstream & Downstream
manufacturing & bioprocessing
Sep 3014:20
Conference pass

Generative AI for Protein Design

AI & ML, sponsored by Ailux
antibodies
immunotherapy
Sep 3014:20
Conference pass

IL-2/anti-IL-2 antibody fusion proteins as novel selective stimulators of effector cell populations for cancer immunotherapy

Protein Engineering
antibodies
Sep 3014:20
Conference pass

Stimulating collaborations across the ecosystem to advance the impact of cutting-edge patient treatments

Antibodies for Immunotherapy
antibodies
immunotherapy
  • The importance of innovation ecosystems to advance research into real-world applications
  • How to stimulate collaborations in deep tech for patient treatments
  • Building strong and resilient innovation ecosystems
Sep 3014:20
Conference pass

The Evolving Landscape of Cell and Gene Therapies: Insights into Current Developments and Future Prospects

Cell & Gene Therapy
Sep 3014:20
Conference pass

Title TBA

AI & ML, sponsored by Ailux
antibodies
immunotherapy
Sep 3014:20
Conference pass

Title TBA

Clinical Development & Operations
Narendra Maharaj, Head- Clinical Development, Biologics, Dr Reddys Laboratories Limited
Sep 3014:20
Conference pass

Treating Solid Tumors

Targeting the Tumor Microenvironment
immunotherapy
Carmen De Santo, Cruk New Investigator Fellow, Cancer Research UK
Sep 3014:40
Conference pass

Cutting Through the Hype: Real-World Applications of AI in Antibody Discovery and Engineering

AI & ML, sponsored by Ailux
antibodies
immunotherapy

Senior Representative, Ailux

Sep 3014:40
Conference pass

Enhanced vector technology for improved expression control of bispecific antibodies

Bispecifics & Multispecifics

Senior Representative Lonza

Sep 3014:40
Conference pass

Introducing a novel peptide linker technology for the direct modification of antibodies

Armed Antibodies
antibodies
Sep 3014:40
Conference pass

STAb-T Immunotherapies: Novel Delivery Strategies for Bispecific T Cell Engagers in Cancer

Cell & Gene Therapy
Luis Alvarez-Vallina, H12O-CNIO Cancer Immunotherapy Clinical Research Unit, Spanish National Cancer Research Centre (CNIO)
Sep 3014:40
Conference pass

Title TBA

Protein Engineering
antibodies

Senior Representative, Specifica, an Iqvia Company

Sep 3014:40
Conference pass

Title TBA

CMC & Developability
antibodies

Senior Representative, Nanotemper

Sep 3014:40
Conference pass

Title TBA

Antibodies for Immunotherapy
antibodies
immunotherapy

Senior Representative, Genovac Antibody Discovery

Sep 3014:40
Conference pass
Sep 3015:00
Conference pass

A critical look at acid-catalyzed deamidation, peptide solubility and other challenges in conventional Multi-Attribute Method (MAM) workflows – potential pitfalls and solutions

CMC & Developability
antibodies
Sep 3015:00
Conference pass

Artificial intelligence methods to detect dengue-specific antibody repertoire and sequence patterns

AI & ML, sponsored by Ailux
antibodies
immunotherapy
Enkelejda Miho, Professor Of Digital Life Science Sciences, University of Applied Sciences Northwestern Switzerland
Sep 3015:00
Conference pass

Engineering human cytokines for therapy

Protein Engineering
antibodies
Matthias Feige, Technical University Munich
Sep 3015:00
Conference pass

Improving ADC development: high-throughput and in-depth characterization of ADCs by high-resolution mass spectrometry

Armed Antibodies
antibodies

Antibody-drug conjugates (ADCs) are targeted biopharmaceuticals that combine potent cytotoxic drugs with highly selective monoclonal antibodies to deliver chemotherapy specifically to cancer cells, reducing damage to healthy tissue and minimizing side effects. This allows for higher drug doses and increased efficacy. However, ADCs with lysine or cysteine conjugation sites are highly heterogeneous, making their characterization challenging. Determining conjugation sites accurately is key to effective targeting. The drug-to-antibody ratio (DAR) also impacts efficacy, safety, and therapeutic potential. High-resolution mass spectrometry is essential for characterizing ADCs, providing data on conjugation sites, molecular weight, stability, and impurities, and aiding in optimization and quality control.

In the present study, we have developed two analytical workflows for the characterization of ADCs:

1. High-Throughput SEC-MS Workflow: This approach operates under native conditions, enabling rapid analysis of drug load distribution and DAR via fully automated data processing.

2. High-Resolution RPLC-MS/MS Workflow: This method facilitates precise determination of conjugation sites, quantification of site occupancy, and analysis of other post-translational modifications.

In a forced degradation analysis, we demonstrated that exposure to elevated temperature stress significantly impairs both the DAR and the conjugation site, highlighting the vulnerability of ADCs under stress conditions. In addition to the detailed assessment of conjugation site occupancy, we were also able to identify and quantify several critical quality attributes (CQA) of the antibodies, including several deamidation and oxidation sites. These results provide valuable insights into the stability and integrity of ADCs and emphasize the importance of stringent quality control in the development process.

With our approach, we show that these analytical workflows are very well suited for both high-throughput and comprehensive characterization of lysine- and cysteine-conjugated ADCs and can be transferred to ADCs with other conjugation strategies. In general, this approach can be used in the development process of ADCs for the comparison of production batches, stability studies and forced degradation analyses for quality control and assurance.

Sep 3015:00
Conference pass

Preclinical Development of MGC028, an Exatecan-bearing ADC for the Treatment of ADAM9+ Solid Tumors

Antibodies for Immunotherapy
antibodies
immunotherapy
Sep 3015:00
Conference pass

Repolarization and redirection of macrophages for tumor eradication

Bispecifics & Multispecifics
Felix Meiser, PhD student, TU Darmstadt
Sep 3015:00
Conference pass

Title TBA

Clinical Development & Operations
Sergio Leal, Director, Clinical Development Ophthalmology, Bayer Consumer Care AG
Sep 3015:20
Conference pass

Applying AI to expedite biologics development and readiness for FDA/EMA reviews

AI & ML, sponsored by Ailux
antibodies
immunotherapy

Drug developers are integrating analysis by AI tools into their pipeline to expedite the selection of the best targets for development - The use of AI speeds the selection of the best candidates and reduces costly in vitro assays. We can provide data on the accuracy of AI tools and comparisons to other methods such as MAPPS, as well as discuss the use of model master files (referral to existing MMF) in approach to the FDA.

Anne De Groot, Chief Executive Officer, EpiVax Inc
Sep 3015:20
Conference pass

Attenuated cytokine antibody fusions for enhanced anti-tumor activity

Antibodies for Immunotherapy
antibodies
Felix Geyer, PhD student, TU Darmstadt
Sep 3015:20
Conference pass

Development and Dissemination of affordable cell based immunotherapies for low income countries

Cell & Gene Therapy
Sep 3015:20
Conference pass

Developments at Phenomic

Targeting the Tumor Microenvironment
immunotherapy
Sam Cooper, Co-Founder, Phenomic AI
Sep 3015:20
Conference pass

Innovative Approaches in Cell Line Development: Leveraging Technology and Case Studies for Scalable Process Optimization

CMC & Developability
antibodies

Senior Representative Lonza

Sep 3015:20
Conference pass

Regulatory Harmonization for Biosimilars: Global Challenges and Opportunities

Regulation
biosimilars
late stage development

  • The role of clinical studies in biosimilar approval.
  • Variability in biosimilar regulations across different regions and its impact on development.
  • Opportunities for regulatory alignment to streamline approval processes and global access.
  • Addressing challenges in pharmacovigilance and post-approval requirements for biosimilars.

Manal Almutairi, Senior Expert Clinical Assessor, sfda
Sep 3015:20
Conference pass

The Tubutecan Platform – Technology Enabled Payload Solutions Targeting Topoisomerase-I: Preclinical Data for Solid Tumor Targeting ADC Candidates TUB-030 and TUB-040

Armed Antibodies
antibodies
Sep 3015:20
Conference pass

Ti Human Antibody Discovery and Engineering: The Adimab Way

Protein Engineering
antibodies

This presentation will explore how Adimab has revolutionized therapeutic antibody discovery, growing from an innovative startup into a leading platform technology company. We will examine key technological breakthroughs in our platform development, focusing on synthetic antibody library evolution, advances in multispecific antibody generation, and novel approaches to antibody developability optimization. Through specific examples, we will demonstrate how our engineering solutions have enhanced therapeutic candidates and improved their potential for success. Join us to learn how Adimab's systematic, engineering-driven approach is shaping the future of antibody therapeutics.

Sep 3015:20
Conference pass

Title TBA

Antibodies for Immunotherapy
antibodies
immunotherapy

Senior Representative, Acro Biosystems

Sep 3015:40
Conference pass

A machine learning-driven approach for the multi-parametric optimisation of T-cell engagers

AI & ML, sponsored by Ailux
antibodies
immunotherapy

T-cell engagers (TCEs) promise breakthroughs in the treatment of solid tumors, but their progression in the clinic is limited by on-target, off-tumor toxicity. In this talk, I describe how our platform integrates active learning, automation, and high-throughput functional assays to efficiently identify highly selective and potent TCEs. I highlight our utilization of the design-build-test-learn ecosystem to generate high-quality data that powers our machine learning models and therapeutic assets.

Sep 3015:40
Conference pass

A next generation ADC for Nectin-4 expressing tumors: preclinical characterization of IPH45, a novel and differentiated exatecan-based ADC targeting Nectin-4

Armed Antibodies
antibodies
Sep 3015:40
Conference pass

Design of novel antibody therapies for solid tumours: Insights from studying the patient immune response and tumour vulnerabilities

Antibodies for Immunotherapy
antibodies
immunotherapy
Sep 3015:40
Conference pass

From In Vitro Discovery to Modular Protein-Protein-Conjugation: Combinatorial Assembly of Bispecific Antibodies

Protein Engineering
antibodies
Andreas Stengl, Team Lead, Protein Engineering, Ludwig Maximilians University Munich
Sep 3015:40
Conference pass

Generating potent CAR T-cells for targeting solid tumours

Cell & Gene Therapy
Marc Davies, VP, R&D, Leucid Bio
Sep 3015:40
Conference pass

Title TBA

Targeting the Tumor Microenvironment
immunotherapy
Sep 3015:40
Conference pass

Title TBA

CMC & Developability
antibodies
Martin Bertschinger, Director Drug Substance Development, Ichnos Glenmark Innovation
Sep 3016:10
Conference pass

Title TBA

Showcase
showcase

Senior Representative, Entegris

Sep 3016:30
Conference pass

Vytal®: The ready-to-use snap-fit system for container closure solutions, setting the standard for the future.

Showcase
showcase

In recent decades, the landscape of parenteral drug production has undergone significant transformation, driven by the emergence of novel molecules and advanced therapies. The pharmaceutical industry has witnessed a notable shift towards biologics, mAbs, and cell-based therapies, which now represent some of the most successful pharmaceutical products globally.

The production of biotherapeutics presents unique challenges due to their inherent instability and specific containment requirements. This has necessitated a fundamental reimagining of manufacturing processes, with aseptic filling becoming essential in modern pharmaceutical production.

Vytal®, an innovative RTU snap-fit closure is specifically designed for small to medium-batch production of advanced therapeutics, including biologics, viral vectors, mRNA, antibody-drug conjugates, cell & gene therapies and orphan drugs.

Developed under ISO13485 and GMP Annex I requirements, Vytal® offers:

· Snap-fit system

· Ready-to-use

· Glass & COP vial compatibility

· CCI assured even at low temperature (-80 °C)

· Compatibility with standard marketed CSTDs

· ISO dimensions

· Nested & Bulk

· Full visibility

· Reduced particle generation

· Low residual volume

· Anti-counterfeiting: Tamper-evident features & laser marking

Vytal® helps pharmaceutical companies accelerate time-to-market while maintaining high-quality standards, meeting the demands of modern filling technologies and competitive market pressures.

Sep 3016:50
Conference pass

Beyond the Protocol: Key Steps for a Successful and Timely First Clinical Trial

Clinical Development & Operations
  • Quality Management System: Implement robust processes to ensure consistency and compliance
  • Clear Project Management: Align timelines and budget from planning through execution
  • Strategic Framework: Define trial objectives, resources, and collaboration essentials for success
Sep 3016:50
Conference pass

Engineering of bispecific antibody-based IL-12 mimetics with biased agonism capacities

Bispecifics & Multispecifics
Sep 3016:50
Conference pass

Optimizing Antibody Expression: ATUM’s Leap-In Transposase® Technology for Stable and Scalable Biologics Manufacturing

CMC & Developability
antibodies

As the demand for high-quality biologics accelerates, biopharmaceutical developers face increasing pressure to optimize cell line development for speed, quality, stability, and scalability. ATUM’s Leap-In Transposase® technology is transforming the landscape of protein expression by enabling rapid, predictable, and high-yield stable cell line generation. Unlike traditional gene of interest integration methods, the Leap-In Transposase® system facilitates highly efficient transgene integration at transcriptionally active loci, leading to enhanced expression, improved genetic stability, and accelerated development timelines.In this presentation, we will showcase how the technology is empowering biopharma teams to achieve faster workflows while minimizing the need for labor-intensive single-cell cloning. We will present case studies demonstrating its impact across monoclonal antibodies, multispecifics, and novel therapeutic proteins, highlighting significant improvements in titers, scalability, and manufacturability. Furthermore, we will discuss its seamless integration with CHO and HEK cell systems, making it an ideal solution for both early-stage discovery and commercial-scale production.

Sep 3016:50
Conference pass

Robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds

Protein Engineering
antibodies
Sep 3016:50
Conference pass

The Therapeutic Potential of IgE and IgE-derived Antibodies

Antibodies for Immunotherapy
antibodies
immunotherapy
Sep 3016:50
Conference pass

Title TBA

Armed Antibodies
antibodies

Senior Representative, Tubulis

Sep 3017:10
Conference pass

Bifunctional antibody derivatives for immune system manipulation

Bispecifics & Multispecifics
  • Generation and characterization of single-domain antibody derived bispecifics
  • Mimicking the function of a cytokine by triggering agonism on its receptor
  • Antibody engineering to further improve the agonism

Sep 3017:10
Conference pass

Sane in the membrane - Discovery of antibodies against challenging membrane protein targets using Salipro nanoparticles

Protein Engineering
antibodies
Sep 3017:10
Conference pass

The Path to Enlightenment: Strategic Photostability Testing & Light Mapping in Fill & Finish Operations

CMC & Developability
antibodies
  • Photostability Studies in CMC Development: Strategic implementation of forced degradation and confirmatory photostability testing at critical development milestones to identify light-sensitive products and establish appropriate protection requirements.
  • Comprehensive Light Mapping Methodology: Systematic approach to quantify light exposure across fill and finish operations, focusing on critical processing areas where product is most vulnerable to photodegradation.
  • Risk Mitigation Strategies: Development of effective light protection measures based on photostability data and light mapping results, including facility modifications, process adjustments, and monitoring protocols.
Sep 3017:10
Conference pass

Title TBA

Armed Antibodies
antibodies

Senior Representative, BSP Pharmaceuticals

Sep 3017:10
Conference pass

Title TBA

AI & ML, sponsored by Ailux
antibodies
immunotherapy

Senior Representative, ABSCI

Sep 3017:30
Conference pass

Directed Luck®: Transposase targeting and Transposon design push expression beyond limits

CMC & Developability
antibodies

Transposases have eased cell line development. Taking this concept to a new level, we equipped our hyperactive transposase with epigenetic readers that targets highly active genomic sites in the host cell line and designed advanced transposons with optimized ITRs for most efficient and clean integration. DirectedLuck® delivers highly productive clones and bulk pools ready for manufacturing and is particularly suited for heterodimeric formats, polyclonal antibody cell lines and viral vector packaging cell lines.

Sep 3017:30
Conference pass

Title TBA

Protein Engineering
antibodies

Senior Representative, Bio-Rad

Sep 3017:30
Conference pass

Title TBA

Antibodies for Immunotherapy
antibodies
immunotherapy
Sep 3017:30
Conference pass

Unveiling the PanCancer potential of dual-mechanistic uPAR-targeting ADCs across cancers

Armed Antibodies
antibodies

Currently, most approved antibody-drug conjugates (ADCs) target tumor-associated antigens. However, this approach hinders effective treatment of solid tumors, particularly those with a dense stromal microenvironment, like pancreatic cancer (PDAC), where the tumor stroma contributes to disease progression, immunosuppression, and drug resistance. To address this challenge, we have developed PanTarg, a novel ADC designed to target both cancer cells and the surrounding stromal environment. PanTarg specifically targets the urokinase plasminogen activator receptor (uPAR), which is overexpressed in both the tumor and stromal compartments of many aggressive cancers, particularly PDAC, with limited expression in normal tissues. This dual-target strategy aims to overcome stromal barriers and expand the range of indications and patient populations that can benefit from ADCs. PanTarg is based on a proprietary uPAR antibody with optimal ADC properties. In preclinical models of PDAC and other uPAR-positive tumors, PanTarg has demonstrated strong anti-tumor and stromal effects, bystander and immune modulatory activities, and good tolerability. These promising results validate uPAR as a compelling ADC target and position PanTarg as a potential new therapeutic option, either as a monotherapy or in combination therapies.

Sep 3017:50
Conference pass

Developing Avidity-driven Tumour Selective Multispecific Antibodies

Bispecifics & Multispecifics
antibodies
Dan Foxler, Head of Cell Biology, LabGenius Tx
Sep 3017:50
Conference pass

eIg-based bispecific T-cell engager: Format matters

Antibodies for Immunotherapy
antibodies
immunotherapy
Sep 3017:50
Conference pass

HDPs ADC Payload Toolbox – Multiple Options to Fight Cancer

Armed Antibodies
antibodies
Sep 3017:50
Conference pass

NANOBODY® VHH as a modality for Targeted Protein Degradation

Protein Engineering
antibodies
Sep 3017:50
Conference pass

Create your personal agenda –check the favourite icon

Oct 19:55
Conference pass

Bispecific and multispecific antibodies: An overview of development trends and the current clinical pipeline

Keynotes
antibodies
immunotherapy
biosimilars
manufacturing & bioprocessing
clinical trials

Dr. Crescioli will provide a comprehensive analysis of the latest trends in the commercial clinical development of bispecific and multispecific antibodies. She will review trends in their mechanism of action, format and targets, and she will provide an overview of both early and late stage clinical pipeline.

Oct 111:00
Conference pass

Title TBA

Showcase
showcase

Senior Representative, Cytiva

Oct 111:20
Conference pass

Advancing Therapeutic Oligonucleotide Manufacturing: Oligo Factory’s GMP Solutions for Clinical Success

Showcase
showcase

The increasing demand for high-quality oligonucleotides in therapeutic applications necessitates scalable, efficient, and compliant manufacturing processes. Oligo Factory is at the forefront of this demand, offering ICH Q7 GMP-compliant oligonucleotide manufacturing with a focus on therapeutic oligonucleotides such as ASOs, siRNA, aptamers, and guide RNAs. This presentation will highlight Oligo Factory’s proprietary synthesis platform, scalable production capabilities, and comprehensive analytical services designed to meet rigorous regulatory standards.

Attendees will gain insights into how our U.S.-based and sourced GMP facility streamlines oligonucleotide manufacturing, ensuring the highest quality, rapid turnaround times, and flexible support from late discovery through clinical phases. In addition, we will explain our key process optimizations that enhance efficiency and consistency, enabling the reliable production of complex oligonucleotides for therapeutic development. Join us to explore how Oligo Factory is advancing the next generation of oligonucleotide-based therapies.

Oct 111:45
Conference pass

Roundtables

Roundtables
Current perspectives on agonists targeting the co-stimulatory members of the TNFRSF (CD27, 4-1BB, Ox40, GITR; LTBR)
General Inception - A venture capital firm that partners with innovators to nurture groundbreaking ideas across the biotechnology sector
Laure Bouchez, Executive in Residence, General Inception
Sponsored by FUJIFILM Diosynth
Sponsored by Genedata
Sponsored by Nona Biosciences
Oct 113:00
Conference pass
Oct 114:00
Conference pass

Biosimilars in Denmark: Easy market access, high uptake, increased patient care and sustainable health care budgets.

Market Access: Sustainability & Commercialisation
biosimilars
Oct 114:00
Conference pass

Insights into the future of Gene Therapy

Cell & Gene Therapy
Oct 114:00
Conference pass

Molecular prediction and monitoring of clinical response to anti-PD-1/anti-PD-L1 immune checkpoint inhibitors: new perspectives for precision medicine and mass spectrometry-based investigations.

Antibodies for Immunotherapy
antibodies
immunotherapy
Oct 114:00
Conference pass

Predicting Intestinal Therapeutic Protein-Target Engagement in Inflammatory Bowel Disease with a Minimal Physiologically-based Pharmacokinetic (PBPK) Model

Autoimmune Disorders and Inflammation
antibodies
Oct 114:00
Conference pass

Prediction of antibody developability properties at scale

In Silico & Computational Discovery and Development
antibodies
  • We developed machine learning models to efficiently predict key antibody developability properties.
  • Predictions can be scaled up to process large numbers of antibodies.
  • Our models can be used in a multi-objective optimisation setting.
Andrei Kamenski, Senior Data Scientist, In Silico Antibody Discovery, Novo Nordisk
Oct 114:00
Conference pass

Selective Human Receptor Modulating Peptides for GPCR agonism and antagonism

Protein Engineering
antibodies
David O'Connell, Associate Professor, School Of Biomolecular And Biomedical Science, University College Dublin
Oct 114:00
Conference pass

Title TBA

Checkpoint Inhibitors
immunotherapy
Hilmar Ebersbach, CSO, Immunos Therapeutics
Oct 114:00
Conference pass

Title TBA

Patient Engagement and Study Activation
clinical trials
Oct 114:00
Conference pass

Title TBA

Translational Medicine
immunotherapy
Ahuva Nissim, Professor, Queen Mary University
Oct 114:00
Conference pass

Translating Bispecific Costimulatory Antibodies into First-in-Human Trials: Bridging Preclinical Development to Clinical Application

Translational Medicine
immunotherapy
Oct 114:00
Conference pass

What makes your antibodies happy if not (anti-)genius purification

Bioprocessing: Upstream & Downstream
manufacturing & bioprocessing
Oct 114:20
Conference pass

Improved Antibody Discovery using High-Density Antigen Display with Engineered Virus-Like Particles

Protein Engineering
antibodies

Senior Representative, Icosagen

Oct 114:20
Conference pass

Revisiting Biomarkers in Lupus Nephritis

Autoimmune Disorders and Inflammation
antibodies
Oct 114:20
Conference pass

Title TBA

Translational Medicine
immunotherapy
Oct 114:20
Conference pass

Title TBA

Checkpoint Inhibitors
immunotherapy
Stephen Beers, Professor of Immunology and Immunotherapy, University of Southampton
Oct 114:20
Conference pass

Title TBA

Patient Engagement and Study Activation
clinical trials
Lorenz Tanner, Member of Patient Board, SAKK Swiss Group for Clinical Cancer Research
Oct 114:20
Conference pass

Title TBA

Cell & Gene Therapy
Alexander Dityatev, Group Leader, German Ceter for Neurodegenerative Diseases (DZNE)
Oct 114:40
Conference pass

Anti-tau immunotherapy targeting the core demonstrates potential best-in-class potency for indication of Alzheimer’s disease and other tauopathies.

Antibodies for Immunotherapy
antibodies
immunotherapy
Oct 114:40
Conference pass

Challenges of Viral Clearance in a Downstream AAV Process and future directions

Bioprocessing: Upstream & Downstream
manufacturing & bioprocessing
Oct 114:40
Conference pass

Panel Discussion: Finance & Investment for Start Ups

Finance & Investment
antibodies
immunotherapy
biosimilars
manufacturing & bioprocessing
clinical trials
Sascha Oliver Buchner, Co-Founder and Partner, Forty51 Ventures AG
Oct 114:40
Conference pass

Title TBA

In Silico & Computational Discovery and Development
antibodies

Senior Representative, Schrödinger

Oct 114:40
Conference pass

Title TBA

Checkpoint Inhibitors
immunotherapy
Tomasz Sitar, Head of CMC at JJP Biologics, JJP Biologics
Oct 114:40
Conference pass

Title TBA

Market Access: Sustainability & Commercialisation
biosimilars
late stage development
Oct 114:40
Conference pass

Unlocking Precision: The Versatility of Athebody Platform for targeted Therapeutics

Protein Engineering
antibodies
Thomas Huber, Athebio
Oct 115:00
Conference pass

Title TBA

Protein Engineering
antibodies

Senior Representative, Kactus

Oct 115:00
Conference pass

Title TBA

Autoimmune Disorders and Inflammation
antibodies

Reserved for Tridek-One Therapeutics

Oct 115:00
Conference pass

Title TBA

Antibodies for Immunotherapy
antibodies
immunotherapy
Oct 115:20
Conference pass

Clinical Trial Design and Regulatory Considerations for Hematological Gene Therapies

Patient Engagement and Study Activation
clinical trials
Manal Almutairi, Senior Expert Clinical Assessor, sfda
Oct 115:20
Conference pass

Expanding the use of monoclonals antibodies into cellular immunotherapy

Antibodies for Immunotherapy
antibodies
immunotherapy
Oct 115:20
Conference pass

New opportunities to overcome the efficacy and toxicity problems of immunotherapies with affinity-switchable antibodies

Protein Engineering
antibodies
Oct 116:30
Conference pass

Engineering a multimodal protease inhibitor for respiratory indications

Protein Engineering
antibodies
Ruediger Jankowsky, CEO, AATec Medical GmbH
Oct 116:30
Conference pass

ISB 2001, a First-in-Class Trispecific BCMA and CD38 T Cell Engager Designed to Overcome Mechanisms of Escape from Multiple Myeloma Treatments

Antibodies for Immunotherapy
antibodies
immunotherapy
Maria Pihlgren Bosch, Senior Director, Ichnos Glenmark Innovation, IGI
Oct 116:30
Conference pass

Title TBA

Therapeutic Vaccine Development and mRNA Technologies
immunotherapy
Oct 116:30
Conference pass

Title TBA

Clinical Trial Planning & Design: Data Management
clinical trials
Livnat Halel, Experienced Clinical Projects Manager, Independent
Oct 116:50
Conference pass

Advances in pHLA directed T cell engager discovery and design

Antibodies for Immunotherapy
antibodies
immunotherapy
Oct 116:50
Conference pass

Title TBA

Therapeutic Vaccine Development and mRNA Technologies
immunotherapy
Prasun Chakraborty, Founder and Chief Executive Officer, Genevation LTD
Oct 116:50
Conference pass

Title TBA

Clinical Trial Planning & Design: Data Management
clinical trials
Pieter Voermans, Head Clinical Data Management, Sobi
Oct 117:10
Conference pass

Engineering bispecific sdAb-based antibodies

Protein Engineering
antibodies
Oct 117:10
Conference pass

Title TBA

Therapeutic Vaccine Development and mRNA Technologies
immunotherapy
Cedric Bogaert, Chief Executive Officer, myNEO Therapeutics
Oct 117:30
Conference pass

Biosimilar Sustainability Panel

Market Access: Sustainability & Commercialisation
biosimilars
late stage development
Julie Maréchal-Jamil, Director Biosimilars Policy & Science, Medicines for Europe
Oct 117:30
Conference pass

First-in-class anti-TRPV6 antibody as a new therapeutic agent in oncology

Antibodies for Immunotherapy
antibodies
immunotherapy
Johanna Marines, Head of Preclinical, Mabqi
Oct 117:50
Conference pass

Conquering The Last Frontier: Developing Ion Channel Modulating Antibodies

Antibodies for Immunotherapy
antibodies
immunotherapy

Ion channels are an important target class implicated in several untreated or poorly treated diseases. Despite the unmet need and the potential of monoclonal antibodies (mAbs) in this domain, no mAbs targeting ion channels have achieved clinical approval or are in clinical development. Maxion has shown that small cysteine-rich miniproteins (knottins) with ion-channel modulating activity can be inserted into antibody CDRs to create a novel mAb format called KnotBodies. KnotBodies maintain the ion channel activity of knottins while benefitting from the optimal drug-like properties of antibodies. This presentation will illustrate the discovery and optimisation of KnotBody inhibitors to therapeutically relevant ion channel targets.

Aneesh Karatt Vellatt, Chief Scientific Officer, Maxion Therapeutics
Oct 117:50
Conference pass

Title TBA

Therapeutic Vaccine Development and mRNA Technologies
Oct 117:50
Conference pass

Title TBA

Clinical Trial Planning & Design: Data Management
clinical trials
Nadia Fernandez, Industry Clinical Collaboration Leader, F. Hoffmann-La Roche Ltd.

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Oct 29:00
Conference pass

Formulation development for biologics

Formulation & Fill/Finish
manufacturing & bioprocessing
Eva-Maria Knoch, Senior Scientist II, AbbVie
Oct 210:00
Conference pass

Keynote Panel Discussion: Next Generation Antibody Formats

Keynotes
antibodies

· Exploring the current state of antibody modalities and emerging therapeutics

· Advances in established formats: next generation bispecifics and ADCs

· The potential of AI in antibody engineering – what place does this technology hold in antibody development?

Oct 210:00
Conference pass

Title TBA

Formulation & Fill/Finish
manufacturing & bioprocessing
Oct 211:30
Conference pass

Clinical mass spectrometry

Proteomics & Mass Spectrometry
antibodies
Oct 211:30
Conference pass

How to prevent protein aggregation through stabilizers and surfactants

Formulation & Fill/Finish
manufacturing & bioprocessing
Stefan Braun, Head of Laboratory, Merck Life Science KGaA
Oct 211:30
Conference pass

Small analytical tweaks can help improve the cleaning process in a large manufacturing plant

Analytics, screening and diagnostics
antibodies
Tanima Bose, Senior Principal Scientist, Analytical lead, Novartis
Oct 211:30
Conference pass

Synthetic Genetic Systems for Improving Protein Expression

Antibody & Biosimilar Manufacturing
manufacturing & bioprocessing
Oct 211:30
Conference pass

The Localization of T-cell epitopes in biopharmaceuticals: from peptides to gene therapy vectors

Immunogenicity
antibodies
Oct 211:30
Conference pass
Oct 211:50
Conference pass

Role of automation in Protein mass spectrometry: from lead discovery to bioprocess modeling

Proteomics & Mass Spectrometry
antibodies

Modern biopharmaceuticals, a substantial part of Roche's Large Molecule Research (LMR) project portfolio, are highly engineered, often bispecific proteins that address complex modes of action for disease treatment. Mass spectrometry (MS) is a well-established technology, easily capable of identifying proteins and their potential side products. Automation of protein MS analysis has already been successful in applications that require repeated analysis of samples from one well-characterized protein, e.g., throughout process development of biotherapeutics in clinical development.

This talk will showcase the approach taken by Roche's LMR MS unit to enable high-throughput MS analysis for protein screening or process modeling applications that were previously too demanding due to sample diversity and sample numbers.

Vincent Larraillet, Senior Scientist, Roche
Oct 212:10
Conference pass

In vivo models to predict clinical outcome of multispecific cancer therapeutics

Analytics, screening and diagnostics
antibodies
Stefano Sammicheli, Senior Director, Ichnos Glenmark Innovation
Oct 212:10
Conference pass

Next-generation TCR-like antibodies with improved specificity profiles

Antibodies for Immunotherapy
antibodies
immunotherapy

In this talk, we introduce YUMAB’s advanced TCR-mimic discovery platform addressing the off-target-pHLA binding challenge. Employing our technology, we discovered highly specific, human antibodies against the cancer antigen WT1. Our antibodies outperform established references (e.g., 11D06, ESK1) in affinity and specificity without additional engineering. As a next step, we integrate these TCR-like antibodies with proprietary anti-CD3 antibodies to develop bispecific T cell engagers (“safeTY-engagers”). This innovative approach, funded by the BMBF (safeTY-engager, ID: 16LW0341), aims to enhance precision and safety in cancer immunotherapy.

Oct 212:10
Conference pass

Streamlining Biosimilar Development

Antibody & Biosimilar Manufacturing
manufacturing & bioprocessing
Andreu Soldevila, Chief Executive Officer, SYNA therapeutics
Oct 212:10
Conference pass

Title TBA

Library Development
antibodies
immunotherapy
Juan Carlos Almagro, R&D Director, UDIBI-National Polytechnique Institute
Oct 212:30
Conference pass

Discovery of antibodies that modulate macrophage functions in cancer

Antibodies for Immunotherapy
antibodies
immunotherapy
Jianyong Wang, Senior Principal Scientist, Genentech
Oct 212:30
Conference pass

Mass spectrometry-based biodistribution of biotherapeutics: an alternative to radio-biodistribution

Proteomics & Mass Spectrometry
antibodies
Oct 212:30
Conference pass

Title TBA

Library Development
antibodies
Oct 212:50
Conference pass

Merus Class of Bispecific ADC (ADClonics) to Achieve Improved Binding Selectivity, Internalization, and Tumor-Cell Killing

Antibodies for Immunotherapy
antibodies
immunotherapy

Giulio Russo, Senior Scientist, Merus (RESERVED)

last published: 14/Apr/25 16:05 GMT