Martinus Capelle | Distinguished Scientist II
Janssen
Martinus Capelle is working at Johnson & Johnson Innovative Medicine as Distinguished Scientist II in the global Drug Product Development & Delivery organization. He is an innovative Drug Product leader and CMC strategist with ~25 years of experience across pre‑clinical to late‑stage development and launch. Expertise spans formulation, biopharmaceutics, advanced analytical development, fill/finish, and manufacturing of biologics, including peptides, proteins, multi-specific mAbs, vaccines, viral, cell-gene therapies and RNA‑LNPs. Holds a PhD in Pharmaceutical Technology (University of Geneva); previously collaborated with multiple biotech/pharma companies at Therapeomic (CRO, Basel) and has held roles of increasing responsibility at J&J since 2012.
Appearances:
Festival of Biologics Day 1 @ 17:50
Rethinking Formulation Development of Biologics
Protein formulation development has traditionally prioritized vial stability, shelf-life, and manufacturability under static conditions — an approach increasingly insufficient for today's high-concentration biologics and subcutaneous delivery formats. This presentation reimagines formulation as a lifecycle discipline that spans from molecule design through to in-vivo performance. High-throughput screening, physiological compatibility testing, and biopharmaceutics-informed strategies can replace narrowly focused stability paradigms. By embedding this integrated mindset early in development, the industry can reduce attrition, lower cost of goods, and improve clinical outcomes.
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