Alvaro Cruz-Izquierdo | Lead Applications Scientist
Ecolab
Álvaro Cruz-Izquierdo is an RD&E Lead Application Scientist at Ecolab. He is a biochemist specialising in the development of downstream processing technologies for the purification of antibodies and recombinant proteins using novel chromatographic resins. Throughout his career in both academia and industry, he has focused on the application of proteins and protein-based technologies for industrial and bioprocessing applications.
Appearances:
Festival of Biologics Day 2 @ 14:30
Impurity control in complex monoclonal antibody purification via next-generation resins
A new wave of monoclonal antibody therapeutics is in development that utilize complex molecular structures as a route to enhanced efficacy. These challenging molecules require new synthetic pathways for their creation, pathways that present unique purification challenges which must be overcome for commercial viability. Increasingly, the choice of affinity resin in the purification workflow is critical to obtaining viable results that can be scaled to commercial volumes. This presentation describes how the unique features of modern affinity resins can be leveraged to create robust purification workflows for even the most challenging molecules.
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