FORMULATION, FILL & FINISH
SPEAKERS INCLUDE
Jean-René Authelin
Global Head of Pharmaceutical Engineering
Sanofi
Tudor Arvinte
CEO, Therapeomic Inc. Basel Professor
University of Geneva
Jennifer McManus
Lecturer, Department of Chemistry,
Maynooth University
Ahmed Besheer
Group Head NBE Formulation Development – Biologics Drug Product Development
Novartis
Lea Ann Dailey
Professor in Biopharmacy
The Martin-uther Univer sität Halle-Witteberg
Shahid Uddin
Head of formulation
Medimmune
FORMULATION, FILL & FINISH
Speaker presentations include:
Formulation – High concentration biologics and advanced formats
Chaired by:
Shahid Uddin
, Head of Formulation,
MedImmune
Formulation and analytical challenges in developing biosimilars
• Importance of orthogonal analytical methods
• Evaluation of different drug substance (DS) manufacturing methods
• Screening of drug product (DP) formulations identical or similar to originator
• Study and comparison of formulation ingredients
• Comparison of different batches of originator and biosimilar DP
• Studies of formulation interactions with human plasma and blood
Tudor Arvinte , CEO, Therapeomic Inc. Basel, Professor, University of Geneva
Aggregation analysis at high and low protein concentrations
• Aggregation of proteins may occur by a number of different mechanisms, which can lead to a range of aggregate types
• Using a range of analytical techniques, the formation of protein aggregates by various mechanism has been assessed at low and where possible, at moderate to high protein concentrations
• The effect of sugars on protein stability will also be discussed
Jennifer McManus , Senior Lecturer in Chemistry, Maynooth University
Formulation – Stability and longevity Adsorption to filter membranes: relevance for administration and manufacturing
• Filtratration is an important processing step, which a formulated biologic can experience at different stages throughout its lifetime (manufacturing of fully-formulated DS and fill and finish for DP, administration in a clinical setting)
• Adsorption to filter membranes is one of the common incompatibilities during DP administration in a clinical setting. Finding correlations can help in simplifying compatibility studies.
• Adsorption to filter membranes during sterile filtration is one of the critical process attributes. Down scale models will be discussed.
Ahmed Besheer , Group Head NBE Formulation Development – Biologics Drug Product Development, Novartis
KEY TOPICS IN 2017
Formulation of high concentration biologics
Formulation of advanced formats
Formulation to ensure stability and longevity
Novel filling technologies
Analytics and quality control for fill and finish
Labelling and logistics
Integrated approaches and processing
WHY SPONSOR?
Since 1988 the world’s leading brands have sponsored Terrapinn’s events. Established brands use our events to consolidate their position, grow their market share, or enter new sectors or territories. Challenger brands use our events to demonstrate thought leadership, establish their point of difference, and win over new customers.
The conference will help you:
Maintain and strengthen existing relationships with key clients and customers
Demonstrate thought leadership, often through speaking positions
Consolidate or raise the profile of their brand
Generate new sales leads
All of these help our clients:
Enter a new territory or a new sector
Consolidate and strengthen an existing position against competition
Grow their market share
Help solve a public relations challenge
Talk to us today about how we can help your business development, marketing and communications plan for 2017 and beyond.
DOWNLOAD THE PROSPECTUS
Download the prospectus to view past attendees, sponsorship opportunities, testimonials, sponsor and exhibition packages, the floorplan and more! Find a package suitable for you at the biomanufacturing & bioprocessing event of the year.
DOWNLOAD THE PROSPECTUS
GET INVOLVED
To sponsor or exhibit contact:
Toby Lomax
Tel: +44 (0)20 7092 1249
email: toby.lomax@terrapinn.com
To speak, contact: Joan Shutt
Tel: +44 207 092 1134
email: joan.shutt@terrapinn.com
Organiser
