Helena Maja Firczuk | Protein Expression Technologies Team Leader
GSK

Festival of Biologics Day 2 @ 16:30

Mammalian highthroughput expression platform (mHTX) for protein reagent generation and beyond

This presentation will cover:

·       Introduction to the mHTX process that allows for design, generation, and expression tests of hundreds of constructs in parallel, followed by purification screen for selected panel of up to 96 molecules.

·       Challenges encountered while developing robust, high-throughput and automation friendly methodologies as well as data capture solutions enabling efficient data mining and reuse.

·       Examples how mHTX was instrumental for delivering both secreted and membrane protein reagents as well as identifying optimal constructs for cellular reagents generation.

Helena Maja Firczuk, Protein Expression Technologies Team Leader, GSK

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Helena Maja Firczuk / Mammalian highthroughput expression platform (mHTX) for protein reagent generation and beyond

Helena Maja Firczuk, Protein Expression Technologies Team Leader,
GSK

I am leading Protein Expression Technologies team at GSK R&D hub in Stevenage, UK. We use automation and HT methodologies to streamline delivery of protein reagents for early drug discovery projects, for both small and large molecule modalities. I have moved to GSK in 2018 after successful...

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