Cradle Bio

Silver Sponsor

Cradle is a software platform for protein engineering, using generative machine learning models to design and optimize protein variants. Cradle customers include 4 out of top-20 global pharma (Novo Nordisk, Johnson & Johnson, …), 2 out of top-5 specialty chemicals (IFF, Novonesis) and 1 out of top-3 agribusiness. Cradle customers report reduced experimental turnaround time to hit protein design goals between 1.5x and 12x. All IP on sequences generated through the Cradle platform are yours and Cradle only charges an annual license fee for use of the platform (no royalties and no milestone payments). Cradle recently raised $73M Series B and raised $100M+ in total.

Cradle recently won the Adaptyv Bio antibody design competition where 130 teams across industry and academia competed to create novel EGFR-binding proteins. 1,131 designs were submitted in total; Cradle submitted 12 designs, all of which outcompeted all other designs of the competition (!) and 3 of which were sub-nanomolar binders. We're happy to schedule a deep dive to go deeper on this external benchmark and other antibody case studies (e.g. multi-property optimization use cases).