Stephen D Pickett has degree in Chemistry from Keble College, Oxford and a PhD from the Royal Institution of Great Britain/Imperial College, where he studied under Professor Sir John Meurig Thomas on the adsorption and diffusion of small molecules in zeolites using Monte Carlo and Molecular Dynamics methods. Postdoctoral studies followed at the Imperial Cancer Research Fund with Professor Michael Sternberg, studying protein folding including the derivation of a scale for side-chain entropy. From the ICRF he took up a position in computational chemistry at Rhone-Poulenc Rorer and then Roche. Subsequently he moved to GlaxoSmithKline, Stevenage to lead a group involved in the computational chemistry and cheminformatics aspects of fragment based drug discovery, high throughput screening, screening collection design, QSAR, virtual screening and automated compound design. He is a GSK Fellow, the author of over 60 peer-reviewed scientific articles and reviews and is a named contributor on six patent applications.