John Castle | Chief Data Science Officer
Monte Rosa Therapeutics

John brings deep experience building AI/ML-driven computational chemistry, computational biology, and 'omics teams for drug discovery and biomarker development. John is currently the Chief Data Scientist and Information Officer at Monte Rosa Therapeutics.  Previously, he served as Associate Vice President for Translational Sciences at Agenus, Associate Director at Rosetta Inpharmatics/Merck & Co., and Co-Director of the Biomarker Development Center of Translational Oncology at the University of Mainz, Germany. He also established the bioinformatics and genomics department at BioNTech AG, where he pioneered methods for tumor neoantigen identification, revolutionizing neoantigen vaccines.  John studied physics at Rice University in Houston and at the University of Göttingen in Germany, was a Fulbright Scholar at the Australian National University in Canberra and received his Ph.D. in geophysics from the University of Washington in Seattle.