IRUBIS GmbH is a biotech start-up based in Munich, Germany. The company was founded in 2017 with the aim to make inline monitoring of bioprocessing by mid-infrared (MIR) spectroscopy to become the standard in manufacturing of biopharmaceutical drugs. During the past eight years the company has developed an innovative process analytical technology (PAT) for real-time monitoring of bioprocesses. Our PAT, Monipa, consists of a mid-infrared (MIR) spectrometer, a single-use flow cell, and a user-friendly software. Monipa makes it possible to get sensitive and robust measurements. The innovative relative measurement does not require additional, time-consuming calibration model-building for process parameters. Our applications include metabolite and nutrient monitoring in upstream processing, and inline monitoring of excipients and protein concentration in downstream processing.