Posters 2023

Poster Number

Title

Presenter

Real-time binding kinetics on cells

2bind GmbH

Out of the box tools for antibody characterization

2bind GmbH

Pushing new boundaries in preclinical drug development – A case study for long time cancer drug resistance assessment

abc biopply ag

Antibody Design Using Generative AI

Absci Corp

Comparing potential bispecific formats of trastuzumab and a humanized OKT3

Absolute Biotech

Sensitive and Robust CAR Expression Detection using Site-specific Fluorescent Labeled Proteins and Flow Cytometry

ACROBiosystems

Addressing critical factors that condition the successful implementation of a receptor-occupancy assay

Active Biomarkers (a Kcas company)

BINDING KINETICS ON LIVE CELLS TO UNRAVEL HOW EPITOPE BINDING INFLUENCES ANTIBODY-DEPENDENT COMPLEMENT ENGAGEMENT FOR THERAPY OF B-CELL MALIGNANCIES

Adamastor Bioservices

Cell Line Developement

Advanced Instruments

Improving MAbs purification in downstream processes

Agarose Bead Technologies

Advancements in Resin Development: Oligonucleotide Purification with IEX Matrix

Agarose Bead Technologies

Comparability Strategy for an Unprecedented Post-Approval Production Cell Line Change of a Bevacizumab Biosimilar IBI305

Altruist Biologics

Reimagining Protein A Capture for Fast Antibody Processing using Membrane Adsorbers

Altruist Biologoics

High-plex spatial imaging to decipher skin microenvironment complexity

AMKbiotech

Pathways to Antibody Discovery Using the CellestiveTM Platform

Antibody Solutions

Development of Luciferase cell lines allows tumor monitoring with the Ivis Imager®

Antineo

Functional assays on the single cell level: advantages and applications for immune cell killing assays

Arralyze

Unlocking the Future of Molecular Biology: Arxspan BioDrive and Seamless Data Integration

Arxspan

Leap-In Transposase(R) - A New Paradigm of Cell Line Development

ATUM

Development of a real-time assay for tracking the proliferation of IPSCs and IPSC-derived organoids

Axion BioSystems

GD2 CAR T cells engineered using retroviral transduction or CRISPR editing exhibit strong cytolytic potency against glioma stem cells

Axion BioSystems

How AstraZeneca created an automated DNA assembly framework

Benchling

Development of a novel approach for flexible production of viral vector-based vaccines

bespark*bio

TrailBlazer: A Rapid Modular Antibody Assembly Platformv

Bio-Rad

Rapid Generation of Bispecific Antibodies for High-Throughput Screening with SpyLock Technology

Bio-Rad

Pioneer: A Novel Biotherapeutic Antibody Discovery Platform

Bio-Rad

GeoBiologics: A Generative AI Platform for De Novo Antibody Design and Optimization

BioGeometry

A Proven and Reliable Alpaca VHH Antibody Discovery Platform

Biointron Biological USA Inc

Development of high throughput single-B cell antibody discovery platform

Biointron Biological USA Inc

Lyophilised Exosomes for Injection: Formulation Development and Cycle Optimisation

Biopharma Group

Background Membrane Imaging – a valuable alternative for particle detection in biotherapeutics?

Boehringer Ingelheim

Exploring the Immunogenic Potential of Therapeutic Protein Aggregates

Boehringer-Ingelheim

Large-scale Characterization of Drug Candidates Against Transmembrane Receptors using HT-SPR

Carterra

Antibody-drug conjugates: A landscape analysis of recent research advancement

CAS

A high throughput vascularized immunocompetent tumoroid model in standard multiwell plates for precision oncology

Cherry Biotech

Need of Active Feedback mechanism for Risk materials via contact Centre: A patient centric approach

COD Research USA Inc.

Biomolecular interaction analysis by Grating-Couple INterferometry and it's application in Diagnostics and Drug Discovery

Creoptix - Malvern Panalytical

Preclinical efficacy, safety and immunogenicity assessment of the BIMERVAX vaccine in a cynomolgus monkey model of SARS-CoV-2 infection.

Cynbiose

An optimized and validated workflow for developing stable producer cell lines with >99.99% assurance of clonality and high clone recovery

CYTENA

Investigation of new phage display approaches for the discovery of single-domain antibodies against protein natural forms

Danmarks Tekniske Universitet / Technical University of Denmark

The Epitope/Paratope mapping according to Deeptope

Deeptope

Glycosylation-Dependent Stability of an Immuno-Regulatory Protein Complex revealed by Native Ion Mobility Mass Spectrometry and Surface Induced Dissociation

ETH Zürich

Your full-service CRO. We feel responsible.

FGK Clinical Research GmbH

In-vitro validation of Glypican-1 as a potential target for antibody- or CAR-based therapies of triple-negative breast cancer (TNBC)

Fraunhofer IZI

Regulatory approval study for a novel ROR1 CAR-T cell product against hematologic and solid malignancies

Fraunhofer IZI

DEVELOPMENT OF CONFORMATIONAL AND TISSUE SPECIFIC ANTIBODY AGAINST A GPCR AS POTENTIAL DRUG CANDIDATE IN IMMUNO-ONCOLOGY

GCLIPS biotech

Revolutionizing Transient Expression with TurboCHO™: A New Era of Protein and Antibody Production

GenScript Biotech

Complete mAb Stability Characterization: From CHO Cell Line Development to Degraded Polysorbate ID

Halo Labs

Assay to predict cytokine storm risk in patients at risk

Immundnz Ltd.

Assessing the immunotoxicity of clinically approved antibodies ex vivo in a test system mimicking human blood circulation - experience from a cohort of 164 healthy donors

Immuneed AB

Engineering a soluble T cell receptor based bispecific molecule to target HIV infected cells

Immunocore

Early Unwanted immunogenicity risk assessment of Biotherapeutics

ImmunXperts, a Q2 solutions company

An Automated Radical Footprinting Platform for In Vivo Epitope Mapping of Membrane-Bound Antigens

Immuto Scientific

Robust proteins for biomedical applications

Incircular

An In Vivo Therapeutic Antibody Efficacy Evaluation: the Chicken Embryo’s CAM-based Assay

INOVOTION

Immunogenicity of therapeutic antibodies: role of aggregation in T lymphocyte response

INSERM UMR 996

DYNAMIC INHIBITON IN SOLUTION ASSAY (dISA) – INOVATIVE SCREENING PLATFORM FOR DRUG DISCOVERY OF CHALLENGING TARGETS

InSingulo AB

The Challenge of Complexity: Peptide Tools for the Development of Immunotherapies

JPT Peptide Technologies GmbH

Development and Validation of a commercial dsRNA ELISA for the quantification of double-stranded RNA in biological preparations.

Krishgen Biosystems

Development and validation of a novel ELISA for accurate and precise pharmacokinetic analysis of bispecific antibody drug Faricimab.

Krishgen Biosystems

Intraocular cytomegalovirus (CMV) escape from host immunity utilizes central and peripheral tolerance mechanisms - potential for multiple therapeutic targets and diagnostics

Kyushu university

A machine-learning algorithm for the smart selection of excipients during biopharmaceutical formulation development

Leukocare AG

Successful USP small scale optimization & equipment transposition: the way to overcome transfer and supply challenges

LFB Biomanufacturing

A High Performing Easy-to-Use Media and Feed System for CHOK1SV GS-KO® Cell Lines-based Product Manufacturing

Lonza AG

Translational modeling to predict human PK of mAbs with modified FcRn binding

LYO-X AG

AI-based antibody selection as a swift solution in the race against SARS-CoV-2 variants

MAbSilico

Truly silent Fc technology

mAbsolve Limited

The Viscosity Reduction Platform: Enabling Subcutaneous Delivery

Merck KGaA

Accelerating antibody discovery for difficult targets using mRNA immunization and BEACON® single cell technology

MimAbs

Automated workflow for screening of CRISPR- edited cell lines. High throughput screening and analysis of monoclonality

Molecular Devices

AtlaZ as a High-Throughput System for Advanced Functional Cell Analysis to Develop Immunotherapies

Nanion Technologies

A new high-throughput fluorescence cell counter, EVE-HT FL

NanoEntek

Predicting biologics developability

NanoTemper Technologies

Increasing transfectivity by incorporation of ether lipids in mRNA lipid nanoparticles

NovoArc GmbH

Early Stage SLC-Transporter Binder Discovery

Nuvisan ICB GmbH

Targeting oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 as a therapeutic approach for Rheumatoid Arthritis

OncoOne Research & Development GmbH

PoET: A generative model of protein families as sequences-of-sequences

OpenProtein.AI

Identification of overlapping B-cell and T-cell epitopes

PEPperPRINT GmbH

Rapid Discovery of Functional Human Memory B Cell-Derived Antibodies for SARS-CoV-2 Using the Beacon® Optofluidic System

PhenomeX

Delivery of cytotoxic camptothecin derivatives to tumors by OncoFAP-based Small Molecule-Drug Conjugates

Philochem AG

Mass Spectrometry characterization of SP2/0 related Host Cell Proteins in downstream processes: the case of an immunocytokine

Philochem AG

Validation of PBPK-Based Translation to Predict Monoclonal Antibody Pharmacokinetics in Pediatric Populations

Phinc Development

Improving mAbs yield and quality through plasmid engineering

Polyplus

DirectedLuck for Bispecifics – A transposase system streamlines cell line development with product quality focus.

ProBioGen AG

Cell-Based Luminescent Reporter Bioassays for Immunotherapies Targeting Macrophage Effector Functions

Promega Corporation

Automated Spectrum Annotation and Structure Disambiguation of Released N - linked Glycans

Protein Metrics

A Fully Integrated and Automated Platform for Screening Biologics

Protein Metrics SA

Interlaboratory evaluation of a user-friendly benchtop mass spectrometer for Multi-Attribute Monitoring studies

Quality Assistance

Optimization of a C-terminal tag for production, purification and site-directional functionalization of VHH

QVQ

Pushing the development of anti-idiotypic VHH through immunization and/or panning

QVQ

Making Better Drugs in Microgravity

Redwire

Development of a monoclonal antibody targeting senescent cells in cancer

Rejuveron Senescence Therapeutics

The development and qualification of liquid adsorption chromatography for poloxamer 188 characterization

Roche

Antibody Discovery Using the Galaxy® Library Platform

RxBiologics

Discovery of Novel Therapeutics Against GPCRs, Ion Channels & Transporters with the Salipro Platform

Salipro Biotech AB

S-DUAL™: A Novel Bispecific Antibody Scaffold withEnhanced Heterodimer Formation and Manufacturability

Samsungbiologics

Discovery of a new versatile E3 ligase for intracellular antibody-based degraders

Sanofi

Ocrelizumab level and anti-ocrelizumab antibodies are associated with B-cell count in multiple sclerosis patients

Sanquin

Biased anti-idiotype response in rabbits leads to high-affinity monoclonal antibodies to biologics

Sanquin Diagnostic Services

100

Barcoding Samples to Facilitate Multi-Sample Measurement in One Flow Cytometry Tube: a Proof-of-Concept Study

Sanquin Diagnostic Services

101

Verification of the unique functionality of ATOR-1017 by 3D structure determination

SARomics Biostructures

102

Structural insights for two Fab – Antigen complexes – Platelet glycoprotein VI and SARS-CoV-2 receptor binding domain

SARomics Biostructures AB

103

Integrated Platform for High-Throughput Media Optimization for CHO cell lines

Sartorius

104

DEVELOPMENT OF AN IN VITRO TESTING PLATFORM FOR BIOSIMILAR THERAPEUTIC MONOCLONAL ANTIBODIES

Selvita S.A.

105

Analysis of AAV loading status by svAUC – GMP compliant

Solvias

106

ATMP - Oligonucleotides and AAV analytics at Solvias

Solvias AG

107

Addressing Brain Metastasis

T-Oncology AG

108

duraTAG - a platform biotechnology for the production of next-generation biopharmaceuticals

Technical University Munich

109

Advanced tools for characterizing diverse bispecific antibodies formed through fusion of single-domain antibodies onto IgG scaffolds

Technical University of Denmark

110

Reducing antibody development time by mammalian cell line engineering and bioprocess optimization

Technical University of Denmark

111

Preclinical Validation of an IL-27a-based Cytokine, as a Next-Generation Immunotherapy

Technical University of Munich

112

Translational Humanized Models for Immunotherapy Drug Development

The Jackson Laboratory

113

SINGLE USE TECHNOLOGY PROCESS SCALE-UP VS. SCALE OUT ENABLED THROUGH NEXT GENERATION BIOREACTORS

Thermo Fisher Scientific-Patheon

114

Advancing Biopharmaceuticals through Innovative CHO Cell Line Development

UGA Biopharma GmbH

115

Bart resolvase mediated synapsis: investigating the mechanism of a novel DNA site-specific recombinase

University of Glasgow

116

Targeting ADAM15 for Rential Neovascular Diseases Using Catalytic Cleft Targeted Antibody Inhibitors

University of Hertfordshire

117

Utilization of activation-induced cytidine deaminase (AID) in mammalian cell display for therapeutic antibody engineering ™

University of Turku / Orion Corporation

118

BIOSIMILARS: Analytical concept for the comparability exercise for mAbs

VelaLabs GmbH

119

Establishment of an Ultra High-Throughput Protein Production Platform (Ultra 96) for Early Stage in vitro Studies

WuXi Biologics

120

Overcoming the Challenges in Asymmetric Bispecific Antibody Production by Using Quick’n Clean Platform

WuXi Biologics

121

Advanced Developability Assessment and Optimization at Early-Stage Discovery for Antibodies

WuXi Biologics

122

Rational Engineering of Antibody Leads into Therapeutics

YUMAB GmbH

123

Droplet microfluidic antibody screening platform for functional antibodies at the single-cell level

École Polytechnique Fédérale de Lausanne (EPFL)

124

Designing and Screening Complex Proteins with Novel Capabilities at Industrial Scale

Genedata

125

Automated Production of Viral Vectors for Cell and Gene Therapy

Genedata

126

Design, Generation, and Evaluation of TCR-, TCR mimetic-, and CAR-based Therapeutics for Cancer Immunotherapy

Genedata

127

Robust and Unbiased New Peak Detection (NPD) in the Multi-Attribute Method (MAM): A Streamlined Data Analysis Workflow

Genedata

128

High-Throughput Identity Testing of Oligonucleotide Therapeutics Using a Fully Automated, Sample-Specific Data Workflow

Genedata

129

Improving Efficiency inDiscovery and Development of Bispecifics and ADCs

Genedata

130

Digitalization Fuels Innovation in Vaccine Research

Genedata

131

Comprehensive Analysis of Nanobody NGS Libraries

Genedata

132

Developing RNA Therapeutics with the Genedata Biopharma Platform

Genedata

133

Automating Assay Data Analysis Along the Antibody Discovery Pipeline

Genedata

134

Analyzing Perfusion Processes in an Integrated Process Development Platform

Genedata

135

High-Throughput Screening for Best Manufacturing Cell Lines using Scale-Down Models

Genedata

136

Measuring the formation of PROTAC ternary complexes with mass photometry

Refeyn

137

Naïve camelid single domain antibody phage display library: A toolbox for identifying functional antibodies for varied applications

Wageningen Bioveterinary Research, Wageningen University & Research

138

Efficient and diverse panel of monoclonal antibodies generation by electro-gene-transfer

Takis Srl

139

Development of pH-sensitive anti-HER2 antibodies to optimize the therapeutic index

Mabqi

140

Structural changes along with disulfide scrambling in stressed monoclonal antibody revealed with DEPC covalent-labeling and quantitative mass spectrometry

CeMOS- HS Mannheim

141

Natural Killer cell heterogeneity, human NK cell repertoires and immunological consequences

National University of Singapore, Immunology Translational Research Programme

142

Development of a new class of target cell lines to evaluate Fc-mediated Cytotoxicity

Svar Life Science AB

143

High-Throughput Intrinsic Fluorescence Analysis for Rapid Thermal Stability Screening of mAbs formulations

Imperial College London

144

High throughput analysis for the next generation of protein biopharmaceuticals

SCIEX

145

Detecting impurities in your lipid nanoparticles (LNP) mRNA biopharmaceuticals

SCIEX

146

Custom-build optimal T-cell engagers for diverse tumor targets with differentiated CD3-binding antibodies

AbCellera

147

Accelerating the path from target to clinic with an integrated antibody discovery and development engine

AbCellera

148

Multi-attribute monitoring of monoclonal antibodies using icIEF-MS

SCIEX

149

High throughput microscale antibodies production and purification to accelerate antibody discovery

Takis Srl

150

Affilin® based Targeted Radioligand Therapy

Navigo Proteins

151

XtalFold™: An antibody-antigen/protein-protein complex structure prediction algorithm with unprecedented accuracy to accelerate therapeutics development

XtalPi

152

XploreSeq™: AI-Enhanced Antibody Discovery Platform via Immune Repertoire Next-Gen Sequencing

XtalPi

153

XuperHuman™: AI-Enabled Comprehensive In Siico Immunogenicity Assessment

XtalPi

154

XrossXeven: AI-Powered GPCR Protein Antigen De Novo Design

XtalPi

155

Enhance and Expand Anti-ID Antibody Diversity and Affinity Through Genetic Immunization

Genovac Antibody Discovery

156

High-throughput Isolation of Functional Antigen Specific Antibodies using Nanovial Technology

Partillion Bioscience

157

RedShift BioAnalytics: Focused on BioAnalytical Characterization from Development to Manufacturing

RedShiftBio

158

Explanding The Scope of The Tripartite β-Lactamase Assay

University of Leeds

159

Targeted protein degradation by antibodies engineered with mannose 6-phosphate analogues

NanoMedSyn

Posters 2023

DEVELOPMENT OF CONFORMATIONAL AND TISSUE SPECIFIC ANTIBODY AGAINST A GPCR AS POTENTIAL DRUG CANDIDATE IN IMMUNO-ONCOLOGY

Created by