Chromatin Bioscience

Startup Plus

Chromatin Bioscience 

We design customised promoters to control cell-type selective gene expression for our clients, i.e., promoters of a certain size, active at a certain level, specific to target cell types, or in response to a stimulus. By mining the genome using our ChromatinLENS® bioinformatics platform we discover and re-purpose natural gene regulatory elements, creating customised gene expression systems to:

Improve human health:

• Creating highly selective and regulatable gene expression vectors for novel gene and cell therapy systems
• Improving the efficiency of biopharmaceuticals production by increasing protein yields in upstream manufacturing processes

Engineer biology:

• Harnessing synthetic biology to make synthetic promoters for a wide array of chassis organisms used in Industrial Biotech
• Creating switches and gene circuits that can be employed in the synthesis of chemicals and pharmaceuticals

Enable traits discovery:

• Creating plant synthetic promoters active across  different crop species for Agricultural Biotechnology applications
• Using plant genomics to facilitate the design of environmentally-regulated and pathogen-inducible  gene expression systems

We have a flexible business model that is tailored to the size and needs of our clients, and to the industry that they operate in. Typically, we charge a technology access fee for our designs, which is then followed by development and commercial milestones.

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