Dr Frank Gesellchen is an Assay Development Manager at Sphere Bio, where he leads the design and optimization of innovative assays for single-cell microfluidic platforms, enabling breakthroughs in antibody discovery, cell line development, and cell therapy research.
Frank earned his Ph.D. in Biology from the University of Heidelberg, specializing in cAMP signalling and protein biochemistry. His scientific career spans research roles in Germany and the UK, where he moved into cross-disciplinary research on lab-on-a-chip devices, before joining Sphere Bio in 2015.
At Sphere Bio, Frank combines deep technical expertise with a drive for translational impact—ensuring assay performance meets the complex demands of modern biopharma workflows.
Sphere Bio’s Cyto-Mine® Chroma advances antibody discovery and cell line development with droplet microfluidics & multi-laser single-cell analysis. Leveraging picodroplet technology, it enables high-throughput screening of cells of interest, accurately sorting and dispensing single cells by productivity & viability, accelerating therapeutic development.
In this talk we will introduce Cyto-Mine® Chroma, highlight its multiplexing capabilities, present applications and assays for use with the platform, and have a look at the road ahead.