Sisa Njikelana is mainly an entrepreneur particularly in the energy industry and enterprise engineering services. He is also the Senior Policy Advisor and Industry Specialist for UNIDO in the South African Industrial Energy Efficiency Project in National Cleaner Production Centre. He was a research fellow at the Centre of Competition, Regulation and Economic Development at the University of Johannesburg from 2015 to 2018. A former Chairperson of SA Independent Power Producers Association. From 2014 until now a Trustee at Studies in Poverty and Inequality Institute and also member of Nuclear Industry Association of SA, Fossil Fuel Foundation and SA National Energy Association. He is also a patron of Production Technologies Association of SA as from August 2019.
A former Member of Parliament (2004 to 2014), he was also Chairperson of the Portfolio Committee on Energy, as well as active in various parliamentary committees. He was educated in the Eastern Cape and later at Ruskin College, Oxford University. He also holds a Certificate in Leadership Communication from Rhodes University. He was a Councillor for three years in the Eastern Metro Local Council in the Greater Johannesburg Metro Council from 1995 to 1998. As a councillor in the former Eastern Metropolitan Local Council, he worked intensively in the Alexandra Development Project from 1995 to 1998. As a member of the Executive Committee he was responsible for Urban Planning and Development. He sits as an executive and non-executive director on a number of boards.