Dr. Mane completed his PhD at The University of Bombay and completed postdoctoral studies at The Johns Hopkins University School of Medicine. He is currently a professor of genetics at the Yale University School of Medicine. As the executive director of The Yale Center for Genome Analysis (YCGA), he has led this center to be one of the most scientifically productive and accomplished Genome Centers in the world. Dr. Mane has published more than 125 papers in reputed journals and served as an ad hock reviewer of several journals. In 2005, his group published the first landmark article in Science after the completion of the human genome, which identified a gene associated with Age Related Macular Degeneration. This publication marked the beginning of the precision medicine era. His group then went on to publish an article in 2009, which was the first to report using exome sequencing as a clinical diagnostic application. Exome sequencing is now used worldwide for both basic research as well as clinical applications. Since joining Yale, he has attracted more than $40 million in funding from both NIH and private sector. He is, also one of the principle investigators of a $12 million grant from NIH/NHGRI to establish The Yale Center for Mendelian Genomics. His current research focus is on Cancer and rare diseases.