Dr. Sonia Gregory leads the Self Amplifying mRNA (SAM) CMC Platform team at GSK Vaccines, which is focused on process and product improvement, scale up, analytical strategy, QbD, rapid response, and acceleration of RNA products. She earned a BS and MS in Chemistry from the University of North Carolina Wilmington and a PhD in Biophysics from the University of Virginia. Sonia identified lead therapeutic molecules for progression into development using biophysical techniques at Merck and later transitioned into Technical Development at Novartis Vaccines now GSK Vaccines, where SAM originated. At GSK she has been a lead contributor on key programs where she optimized formulations, process development, and scale-up processes to enable meeting program milestones and clinical manufacture.