Benjamin Vincent | Assistant Professor, Division Of Hematology And Oncology
U.N.C. Lineberger Comprehensive Cancer Center

Dr. Vincent is Assistant Professor of Medicine, Division of Hematology/Oncology at The University of North Carolina at Chapel Hill School of Medicine, with joint faculty appointments in the Department of Microbiology and Immunology, Curriculum in Bioinformatics and Computational Biology, and Computational Medicine Program. The research goals of the Vincent lab are: 1) To understand the immunobiology of cancer using immunogenomics, and 2) To translate that understanding into improved immunotherapy strategies.  To this end, they have developed computational methods for evaluating tumor immune microenvironment features from whole exome and mRNA sequencing data, including advanced methods for neoantigen prediction and adaptive immune receptor repertoire analysis - These methods have been applied to discover immune features that define tumor molecular subtypes, correlate with clinical outcomes, and highlight the importance of features associated with an antigen-specific adaptive immune response.