Prof Stefan Dübel | Director, Department of Biotechnology
Braunschweig University of Technology

Prof Stefan Dübel, Director, Department of Biotechnology, Braunschweig University of Technology

Dr. Stefan Dübel is full Professor of Biotechnology and Director of the respective department at the Technische Universität Braunschweig, Germany. He further serves as director of the technology transfer unit "Centre for Molecular Engineering" of iTUBSmbH and as consultant to biotech / pharma companies and US/EU goverment institutions. He initiated the "Antibody factory" of the German National Gemome Research Network and is editor of the four volume "Handbook of Therapeutic Antibodies" and other antibody engineering books. He is co-founder of several biotech companies, most recently of the human antibody discovery and antibody engineering company Yumab GmbH.
After obtaining his Ph.D. from the Universitiy of Heidelberg, in 1989 he joined the German Cancer Research Center (DKFZ) where he co-pioneered in vitro antibody selection technologies, resulting in several key inventions including antibody phage display (e.g. US Patent 5849500), human antibody libraries (e.g. US6319690) and antibody libraries with randomised CDRs (e.g. US Patent 5840479). His lab continued to contribute to multiple topics related to human antibody engineering, phage display and in vitro evolution, e.g. Hyperphage technology (2001), ORFeome display (2006), and targeted RNases for cancer therapy (1995/2008). Other achievements include the developed the world's first protein knock down mouse using intrabodies (2014), and a universal allosteric switch module for antibody affinity (2017). His work resulted in >200 publications and >25 patent applications.


EAC 2017 Day 1, Tuesday 31st October 2017 @ 17:10

Panel: Antibody nomenclature and INN strategies

  • Panel to discuss the current confusion surrounding antibody nomenclature
  • Why does the naming system have to be changed?
  • What problems are these causing in the clinic and the lab?
  • Suggestions on how this system can be improved

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