Dr Christian Kleusch | Application Specialist

Dr Christian Kleusch, Application Specialist, NanoTemper

Dr. Christian Kleusch obtained his PhD at the Research Center Juelich, Institute of Bio- and Nanophysics with his research on protein-lipid interactions and plasma membrane modification. Since 2014, Christian Kleusch is working at NanoTemper Technologies as an Application Scientist. He is responsible for introducing and establishing methods such as Microscale Thermophoresis for biophysical interaction characterization, working with customers on their specific projects. He introduced nanoDSF as the method of choice for stability screening and shelf life prediction in 2014 to the european pharmaceutical industry.


EAC 2017 Day 2, Wednesday 1st November 2017 @ 11:25

A better way to characterize monoclonal antibodies with Prometheus

  • Understanding the biophysical properties of monoclonal antibodies can provide powerful insights into screening and characterizing this important class of biologics.
  • Nanotemper-Technologies’ Prometheus platform which performs nano-Differential Scanning Fluorimetry (nanoDSF), a method that provides flexible analysis and ultra-high resolution of protein stability and aggregation will be discussed
  • Utilization of thermal and chemical unfolding as well as aggregation data on monoclonal antibodies can be used as predictive indicators in formulation and stability studies, ultimately resulting in improved biotherapeutic products.

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