Bo Yu | Co Founder and Chief Scientific Officer
Larix Bioscience Llc

Appearances:

Day 1 Antibody Congress @ 15:40

Switchable Membrane Reporter (SwiMR) technology for recombinant protein expression and protein engineering

Plenary

• Switchable Membrane Reporter (SwiMR) technology utilizes a unique switchable reporter system to facilitate FACS-based enrichment and isolation of high producing cells of the protein of interest.
• This eliminates the requirement for gene amplification and reduces cell line screening time from 4-8 months to 2-3 months. 
• The SwiMR technology has been used to generate production CHO cells for multiple antibodies.
• The top clones typically produce 1-4 g/L of antibodies in fed batch culture in commercial media.

Bo Yu, Co Founder and Chief Scientific Officer, Larix Bioscience Llc