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Whitepaper LabChip GXII: Antibody Analysis

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By downloading the white paper you will learn:
 
• Design of Experiment (DOE) studies to test the effect of cell culture changes on post translational modifications of monoclonal antibodies (MAb) or to monitor its purification process, produces large number of samples that can greatly exceed the capacity of modern analytical laboratories.

• LabChip® GXII microfluidics can be used as a high throughput automated alternative to SDS-PAGE and conventional CE- SDS for screening antibody product quality attributes including quantification, fragmentation, and purity analysis. It offers a quick time to result (41 seconds per sample) with < 1% precision.

• The LabChip® GXII is now also being incorporated into formulation and QC departments (without the requirement for high throughput) within the biopharmaceutical industry, expanding on its traditional installation base within clone selection, cell line optimization and protein purification due to robust and sensitive protein assays.