Mary Murphy | Principle Investigator
Remedi National University of Ireland Galway

Mary Murphy, Principle Investigator, Remedi National University of Ireland Galway

Dr. Mary Murphy is Senior Lecturer at NUI Galway and a principle investigator at the Regenerative Medicine Institute (REMEDI). Mary’s research interest and motivation is the development of innovative medicines to treat major diseases using mesenchymal stem/stromal cells (MSCs) or MSCs derived from induced pluripotent stem cells and gene therapy to provide new modalities in patient care for osteoarthritis, bone repair and vascular calcification.  Current clinical research focuses on the therapeutic potential of MSCs and she is involved in the ADIPOA2 Phase 2 clinical trial to assess adipose-derived stromal cells in osteoarthritis. Basic research is focused on the concept that stem cell depletion, or loss/alteration of function, contributes to the development of chronic degenerative diseases such as osteoarthritis and atherosclerosis, the use of the chondrogenic differentiation pathway of bone marrow-derived MSC as a model to study early changes that occur in osteoarthritis development and the role of inflammation and epigenetics in disease progression. Applied research has a focus on the manufacturing of MSCs for therapeutic use and addresses development of novel fully defined serum/medium for cell growth and scale-up for robotic, economic manufacture. She currently coordinates the H2020-funded AUTOSTEM project to develop a GMP-compliant robotic platform for production of clinical grade MSCs.


Advanced Therapies and Regenerative Medicine Day 1 - Wednesday 16th May 2018 @ 14:50

The Autostem project

  • Progress in the fundamental cell biology (isolation, use of novel antibodies etc.)
  • Bioprocessing
  • Automation and how each is brought together

Advanced Therapies and Regenerative Medicine Day 1 - Wednesday 16th May 2018 @ 17:05

Panel discussion: how to approach automation for scaled-up manufacture of cell and gene therapies

back to speakers



Erica Baeta
+44 (0)207 092 1152


Jessica Robinson
t/ +44 (0)207 092 1150


Issa Mauthoor
+44 (0)207 092 1257