Marie-Laure Bas, master in econometrics, is Lean and Six Sigma black belt. She joined Eli Lilly in Fegersheim, France in 1990 in the IT organisation where she led various manufacturing applications development and implementation projects. She discovered MES when implementing the first project in a new parenterals manufacturing building in the mid 90's and has then played the many roles in this arena, from project implementation leader, business Owner, validation and Qa consultant, global support leader, and finally local program manager. Managing cross-functional and cross-cultural teams, she led the implementation program of several local and global MES solutions on the whole plant, in logistics, manufacturing and packaging. Since three years, she acts as a Lean and Six Sigma black belt supporting various organisations of the plant and leading productivity improvement projects.