Britta Eggenreich | PhD Student
Vienna University of Technology

Appearances:

Day 2 Antibody Congress @ 16:41

Production of novel Ab fragments against Celiac’s disease

Plenary

• Inflammatory processes in Celiac’s Disease are in response to dietary gluten and related prolamins uptake
• Novel bivalent tandem single chain Fragment variable (scFv) in E. coli to act as a neutralizing agent during dietary gluten uptake
• Establishing a comprehensive downstream process, consisting of cell disruption, IB wash, solubilization, refolding and product purification to reduce inclusion body effect in e.coli

Britta Eggenreich, PhD Student, Vienna University of Technology