Dr Colin Havenar-Daughton | Scientific Associate
La Jolla Institute for Allergy and Immunology

Dr Colin Havenar-Daughton, Scientific Associate, La Jolla Institute for Allergy and Immunology

Colin joined Shane Crotty's lab at the La Jolla Institute for Allergy and Immunology after a Ph.D. in Immunology from the University of Washington and a postdoc at INSERM in Lyon, France. Most vaccines protect us from infection based on the induction of neutralizing antibodies. I am working to better understand how HIV neutralizing antibodies develop and how to generate them by vaccination. To this end, I am conducting studies in three areas: 1) the T follicular helper (Tfh) and B cell responses that lead to the generation of neutralizing antibodies in individuals infected with HIV, 2) the Tfh and B cell responses induced by candidate HIV vaccines in pre-clinical animal models, 3) the human naive B cell repertoire recognizing candidate HIV vaccines. My goal is to contribute to the development of an HIV vaccine.


Agenda Day 1 @ 12:15

Lymph node fine needle aspirates to reveal correlates for immunization-induced neutralizing antibodies

  • The central role of the germinal center response in generating neutralizing antibodies after HIV Env trimer immunization.
  • The importance of immunization route.
  • Lymph node fine needle aspirates can be used to analyze germinal centers in humans after immunization.

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