Dr. Chen is the Frank M. Calia, MD Endowed Professor of Medicine at the University of Maryland School of Medicine, where he is the Chief of the Division of Geographic Medicine, Department of Medicine. He is an adult infectious disease physician-scientist with a specific interest in developing vaccines against diseases of the impoverished. He is Chief of the Adult Clinical Studies section within the Center for Vaccine Development and Global Health and Director of the UMB Travel Medicine Practice. Dr. Chen is an active investigator within the NIAID-supported Vaccine and Treatment Evaluation Units (VTEUs), consisting of 10 academic centers throughout the U.S. that tackle U.S. prioritized vaccine development. He has been a PI on vaccine trials for: influenza viruses (Seasonal, Pandemic 2009 H1N1, Avian H5N1, and Avian H7N9 influenza), agents of bioterror (Tularemia, Smallpox, and Staphylococcal enterotoxin B), and enteric pathogens (typhoid, Shigella, cholera and enterotoxigenic E. coli). He also develops and conducts human experimental challenge studies, closely monitored infections with well-characterized pathogens, to gain new insights into pathogenesis, the immune response, or early efficacy of candidate vaccines or therapeutics. Among his most important current projects is the clinical development of a Trivalent Salmonella Conjugate Vaccine (TSCV), which is designed to address both Typhoid and the two most common serovars causing invasive non-Typhoidal Salmonella in sub-Saharan Africa.