Principal Investigator. Laboratory of Respiratory and Special Pathogens, Center for Biologics Evaluation and Research, Food and Drug Administration
Dr. Merkel received his Ph.D. from the University of Virginia and received postdoctoral training at the National Institutes of Health before establishing a research program in the Food and Drug Administration. He brings over thirty years of experience in infectious disease research and related disciplines and 18 years of vaccine regulatory experience to the study of bacterial pathogenesis and the evaluation of new vaccines. He has extensive experience developing and utilizing animal models of bacterial infections, including murine and non-human primate models of Pertussis, murine models of Staphylococcal infection, and murine models of Anthrax. The baboon model of pertussis, developed in Dr. Merkel’s laboratory has provided important insights into the host response to both pertussis vaccination and infection. This model continues to provide the pertussis research community with the opportunity to address important questions that shed light on the pathogenesis and vaccine-mediated protection of this important pathogen.