Ramaswamy Kalyanasundaram, PhD, assistant dean for research and head of the Department of Biomedical Sciences at the University of Illinois College of Medicine Rockford, is the professor of microbiology and immunology and is the Michael L. and Susan M. Glasser Endowed Professor. Dr. Kalyanasundaram completed his veterinary medicine from India earned his PhD in parasite immunology from the University of Calgary and postdoctoral training in immunology from the Cornell University. His current research focuses on developing a prophylactic vaccine for lymphatic filariasis, a disabling and disfiguring neglected tropical disease that affects over 120 million people in 72 countries across the tropics and subtropics and another 882 million people are at risk of getting the infection. The lymphatic filariasis vaccine will significantly help in preventing the spread of the infection and will support the global efforts to eliminate the lymphatic filarial infection.
2.10pm – 3.10pm Parasitic disease vaccine development short talks:
4x 15min presentations
2.10pm Hookworm anaemia and malaria combination vaccine development
Dr Peter Hotez, Co-Director, Texas Children’s Hospital Center for Vaccine Development, Baylor College of Medicine
2.30pm Early development of a vaccine against visceral leishmaniasis * Title TBC
Dr Angamuthu Selvapandiyan, Professor, Department of Molecular Medicine, School of Interdisciplinary Studies and Technology, JAMIA HAMDARD
2.50pm Development of vaccines for lymphatic filariasis *Title TBC
Dr Ramaswamy Kalyanasundaram, Department Head, Professor of Microbiology and Immunology, University of Illinois College of Medicine
3.10pm Panel: Challenges in establishing correlates of protection and planning trials for NTD vaccines
· What are the difficulties in establishing COP for NTD vaccines
· Planning for ph2-3 trials – how can we innovate in creating pathways and designs?
Dr Ramaswamy Kalyanasundaram, Department Head, Professor of Microbiology and Immunology, University of Illinois College of Medicine
Michael, Senior Director, Principal Consultant DCS/BPE, Cencora
Additional panelists TBC
4.00pm Panel: Moving the needle: alternative pathways to approval & improving sustainability for global health vaccines (Parasitic & Neglected Diseases)
· Considering pathways to approval in different scenarios – in-country experiences
o Enabling different technology pathways
o From a local manufacturing perspective
· Moving from science to deployment – other than strong data what do we need to move these vaccines forward?
o Understanding incentives for production, government incentives to buy, individual country policies and regulatory requirements
o How is this challenge further compounded with diseases that are not fatal but have high morbidity burden?
o Case studies – Marburg, Hookworm,
· Improving stringency of regulatory agencies through new frameworks
· Can combinations deal with the issue of high burden but low interest? What would be the complications of combining these types of vaccines?
Moderator: Dr Maria Elena Bottazzi, Co-Director of Texas Children’s Hospital Center for Vaccine Development, Baylor College of Medicine
Javier Guzman, Director of Global Health Policy and Senior Fellow, Center for Global Development
Petro Terblanche, Managing Director, Afrigen
Prof Tuck Seng Wong, Professor, Sheffield University; Director, UKSEA Vax Hub
Dr William Hausdorff, Public Health Value Proposition Lead, PATH