Dr Carl Alving | Former Chief of Adjuvant and Antigen Research & Emeritus Senior Scientist
Walter Reed Army Institute Of Research

Dr Carl Alving, Former Chief of Adjuvant and Antigen Research & Emeritus Senior Scientist, Walter Reed Army Institute Of Research

Dr. Alving has been a research investigator at the Walter Reed Army Institute of
Research (WRAIR) in Silver Spring, Maryland, since 1970. His education and
training include a B.S. from Haverford College; an M.D. from University of Miami
Miller School of Medicine; and an internship and residency in medicine and a
fellowship in pharmacology at Barnes Hospital and Washington University in St.
Louis. He served on active duty in the U.S. Army Medical Corps from 1970 to 2000,
and retired as a colonel. At WRAIR He was Chief of the Department of Membrane
Biochemistry from 1978 to 2004, then Chief of the Laboratory of Adjuvant and
Antigen Research (LAAR) at WRAIR until Sept 2017, and he is currently an Emeritus
Senior Scientist at LAAR. He is also an adjunct professor of microbiology and
immunology at the Uniformed Services University of the Health Sciences in
Bethesda, MD.
He developed an early successful application of liposomes as drug carriers for
treatment of leishmaniasis. He is the co‐inventor of the technique of needle‐free
transcutaneous immunization, a technology that is being commercially developed
for vaccination by skin patch. He has been an author or coauthor on more than 300
scientific publications (more than 250 peer‐reviewed papers) in the fields of
adjuvants, antigens, antibodies, complement, lipid biochemistry and immunology,
and liposomes as drug carriers and carriers of vaccines, and he sits on numerous
editorial boards. He has created adjuvants for many types of experimental vaccines,
including vaccines to malaria, HIV, meningococcal infection, heroin addiction,
biological threat agents, and prostate and intestinal cancer. He holds 31 U.S. patents.
His current research interests are focused on vaccines to HIV‐1 infection, malaria,
and addiction to drugs of abuse.
Dr. Alving is a member of the American Association of Immunologists. He was a
founding member of the International Endotoxin Society. He was a founding
member of the International Liposome Society. He was elected chairman of the fifth
Gordon Research Conference on Drug Carriers in Biology and Medicine. In
recognition of his numerous contributions to the liposome field, he was the third
recipient of the Alec Bangham Award for lifetime contributions to liposome
research. He is a Fellow of the American Association for the Advancement of
Science, and a Fellow of the National Academy of Inventors.


DC Plenary Day April 3 @ 09:05

Adjuvant technology and its impact on vaccine development

  • Analysis of the importance and role of innate immunity
  • Formulation of novel adjuvant combinations

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