Rino Rappuoli | Scientific Director
Fondazione Biotecnopolo di Siena

Rino Rappuoli, Scientific Director, Fondazione Biotecnopolo di Siena

Rino Rappuoli is Scientific Director of the Biotecnopolo di Siena Foundation, Italy.  He is also Honorary Professor of Vaccinology at Imperial College, London, and Senior Professor of Molecular Biology at the University of Siena. Prior positions held: Head R&D and Chief Scientist at GSK Vaccines, head of Vaccine R&D at Novartis, CSO at Chiron Corporation, head R&D at Sclavo. He earned his PhD in Biological Sciences at the University of Siena, Italy, and was visiting scientist at Rockefeller University and Harvard Medical School. He is elected member of US National Academy of Sciences (NAS), American Academy of Arts & Sciences (AAAS), American Institute for Medical and Biological Engineering (AIMBE), European Molecular Biology Organization (EMBO), Royal Society of London, Accademia Nazionale dei Lincei. Awards received: Gold Medal by the Italian President, Albert B Sabin Gold Medal, Canada Gairdner International Award, European Inventor Award for Lifetime Achievement, Paul Ehrlich and Ludwig Darmstaedter Prize, Robert Koch Award. He is President of the International Union of Microbiological Societies. He was voted the world's third-most influential person in the field of vaccines at the Terrapinn World Vaccine Congress in 2013. Currently, he is ranked second most important person worldwide in the specialty of vaccines by ScholarGPS.   He has published 836 works in peer-reviewed journals and an H-index of 167. He introduced novel scientific concepts: genetic detoxification; cellular microbiology; reverse vaccinology; pangenome. Developed licensed vaccines: acellular pertussis containing a non-toxic mutant of pertussis toxin; first conjugate vaccine against meningococcus C; conjugate vaccines against meningococcus ACYW, MF59-adjuvanted seasonal and pandemic influenza. MF59 was the first vaccine adjuvant approved for human use after the aluminum salts; meningococcus B by reverse vaccinology; cell culture-based influenza vaccine, respiratory syncytial virus, CRM 197 as carrier of most conjugate vaccines. Founder of the GSK Vaccines Institute for Global Health (GVGH) Professor Rappuoli is among the world scientific leaders dedicated to the sustainability of global health.    

Appearances:



Day 1 - Tuesday 14th October @ 09:05

Keynote Panel: Beyond Borders - Europe’s Strategic Role in Powering Vaccine Innovation and Transforming the Global Vaccine Landscape

  • How can Europe’s unique ecosystem of innovation hubs, regulatory frameworks, and public-private partnerships accelerate the next generation of breakthrough vaccines?
  • What strategies and incentives are needed to transform Europe’s emerging biotechs and SMEs into tomorrow’s vaccine innovation leaders?
  • How can regulatory frameworks evolve to support rapid innovation while maintaining the gold standard in vaccine safety and efficacy?
  • In an increasingly complex global health landscape, how can Europe balance domestic innovation priorities with its responsibility to ensure equitable worldwide vaccine access?

Day 1 - Tuesday 14th October @ 17:00

Keynote Panel: Vaccines & AMR - Turning Commitment into Practical Action

  • How do we channel AMR political commitments into tangible support for early vaccine R&D pipelines 
  • Where is the strongest evidence that vaccines cut antibiotic use, and what data gaps still limit confidence in investment? 
  • Which pathogens and settings should shape the next wave of AMR vaccine innovation beyond the usual priorities? 
  • How do we strengthen the early evidence base so it guides funders, regulators, and developers at the right time? 
  • What collaboration models between funders, small biotechs, and larger pharma can accelerate early-stage research through to viable candidates? 
  • How do we keep fragile AMR vaccine pipelines alive and resilient amid global crises, funding pressures, and competing health priorities? 
last published: 07/Nov/25 11:35 GMT

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