Louise Cosby | Head Of Virology
Agri-Food and Biosciences Institute | United Kingdom

Louise Cosby, Head Of Virology, Agri-Food and Biosciences Institute

Education and Career Professor S. Louise Cosby (SLC) is a graduate (B.Sc. and Ph.D. in Microbiology) of Queen’s University Belfast and was a member of staff for over 30 years. She held the post of Chair of Microbiology in the School of Medicine Dentistry and Biomedical Sciences from 2002 to 2015. She is currently Head of Virology Branch at the Agri-Food and Biosciences Institute in Belfast and emeritus Professor at Queen's University Belfast. Professor Cosby is a Fellow of the Royal College of Pathologists (London) and a Fellow of the Royal Society of Biology (UK). In 1985 she was a visiting Associate Professor in Cornell University USA and has been an occasional visiting scientist at the Pirbright Institute, UK.  Previous/present board membership BBSRC, UK; Science Foundation Ireland (chair/member of Bioscience panel); Professional Development Committee of the Microbiology Society; British Society for Immunology Forum member; Royal Society of Biology, Northern Ireland Committee; Northern Ireland All Party Group on STEM Committee. Editor/Assessor positions: Associate Editor for the Journal of Neurovirology; Review Editor for Frontiers in Microbiology; Assessor roles: appointments and promotions in Medical Microbiology, University of Malaysia; grant applications for European Commission. Research Interests Research has focused on elucidation of pathogenic mechanisms of measles virus (MV), the closely related veterinary morbilliviruses and more recently respiratory syncytial virus. Her study of human tissues from the MV complications subacute sclerosing panencephalitis (SSPE) and measles inclusion body encephalitis has been carried out alongside related work in natural animal hosts and small animal models. Her lab has shown that morbillivirus neurovirulence is related to both the genetic background of the virus and the host as well as immune status of the host. Major interests are in the interaction of viruses with cell receptors as major determinants of virus host range, tissue tropism and induction of disease. This includes investigations into morbillivirus cell entry receptors and interaction of respiratory viruses with transient potential and acid sensing receptors in in vitro models of bronchial epithelium and peripheral nerves. SLC also has interests in new approaches to human and veterinary vaccines and diagnostics. With her team at AFBI and collaborators she is developing and trialling recombinant vaccines using new and established virus large animal challenge models. As Head of Virology Branch at AFBI SLC is responsible for virus contingency molecular diagnostics and delivery of this service in Northern Ireland for epizootic diseases.


Oct 30th Day 2 @ 12:15

Large animal challenge models for assessment of human and veterinary negative strand virus recombinant vaccines

last published: 16/Sep/19 14:05 GMT

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