Amy Shurtleff holds a Ph.D. in Viral Pathogenesis and is Head of Animal Models in the Laboratory Research and Innovations Department in the Division of Research and Development at the Coalition for Epidemic Preparedness Innovations (CEPI). Dr Shurtleff administers research programs for preclinical model development with viral pathogens, and vaccine testing in these models supporting CEPI investment programs. Prior to joining CEPI, she served as the lead research investigator and study director for programs testing DNA vaccines, the Ebola vaccine ERVEBO and other novel vaccine platforms through a long tenure at the United States Army Research Institute for Infectious Diseases (USAMRIID). She has also served as an annual instructor in the UTMB/FDA joint course ‘Achieving Data Quality and Integrity in Maximum Containment Laboratories’, and draws on deep experience in performance of high quality studies performed with emphasis on animal welfare and ethics. She has 20 years of hands on experience in design, development and preclinical testing of antiviral vaccines and therapeutics under high biocontainment with pathogens such as influenza, arenaviruses, hantaviruses, ebolaviruses and coronaviruses.
- Current landscape: overview of emerging alternative approaches, what programmes & strategies are being put in place to adopt alternative approaches to animal use?
- Strategies for integrating these approaches and assessing the reliability and validity of the data obtained; how is this data going to be used to understand disease at the level of R&D?
- Exploring the regulatory framework
- Collaborative efforts and knowledge sharing
- Challenges and future directions for accelerating the adoption of alternative methods