Advent, part of IRBM group


ADVENT is a cGMP Contract Manufacturing Organization (CMO), located in Pomezia within the IRBM campus, and complying with the regulatory guidelines of both FDA and EMA. The GMP facility has been granted the authorization to produce investigational medicinal products by the Italian National Regulatory Authority (AIFA).

ADVENT’s multi-product facility is dedicated to the production of biologic clinical lots. The site is currently focused on adenovirus-based viral vectors, for vaccine and gene therapy applications.

ADVENT’s mission is to maximize quality and cost effectiveness of clinical lot production on behalf of its customers. This is achieved by the outstanding scientific support the team can provide in such areas as analytical method development, process development/validation, in-process assay release setup and qualification and cell banking.

The facility consists of five independent production rooms, a media prep room, a storage area, a purification room and a fill/finish suite. It is designed to provide maximum flexibility and continuity in the manufacturing process. All laboratories are state-of-the-art classified grade C areas with the exception of the grade B fill/finish suite.