Jon Brudvig, PhD, is Senior Director and US Regional Medical Lead for Fabry Disease at Amicus Therapeutics, where he leads medical strategy across Medical Affairs, field medical, and cross-functional teams. His work focuses on advancing understanding of Fabry disease biology, advancing evidence generation, and supporting better outcomes for people living with rare diseases. Jon brings experience across R&D and Medical Affairs, having led programs from early discovery through clinical development. His expertise includes translational science, biomarker development, rare disease strategy, and cross-functional evidence generation efforts. He has authored numerous scientific publications, contributed to multiple therapeutic programs, and is an inventor on several patents related to rare disease therapeutics.