Dr Dafne Mueller | Group Leader, Institute of Cell Culture and Immunotherapy
University of Stuttgart

Dr Dafne Mueller, Group Leader, Institute of Cell Culture and Immunotherapy, University of Stuttgart

Dafne Müller received her doctoral degree from the University of Stuttgart in Germany. At the present she holds a group leader position at the department of Biomedical Engineering at the Institute of Cell Biology and Immunology of the University of Stuttgart. Working in the field of recombinant antibodies for over 15 years, her current research focuses on the development of recombinant antibody-fusion proteins with immune stimulatory or costimulatory properties for targeted cancer immunotherapy.


Day 2 Oct 11th Immune Profiling @ 14:40

Improving the anti-tumor immune response through the use of bi-and trifunctional antibody-cytokine fusion proteins

  • Designing bi- and trifunctional antibody-fusion proteins with IL-15 and costimulatory members of the B7 and TNF superfamily
  • Sharing research which shows enhanced immune responsiveness in vitro and anti-tumour activity in a mouse model in vivo
  • Discussing mode of action employed

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