AGENDA DAY 2

 

Day 2 Oct 11th Immune Profiling

09:00

Chair’s opening remarks

EXCITING IMMUNE-MANIPULATION APPROACHES

Dr Kai Pinkernell
09:10

Development of TCR based adoptive T cell therapies: opportunities and challenge

  • Discovery and Development of T-cells for immunotherapies
  • Identifying patient populations and expanding the responding population
  • TCR targeting of neoantigens
  • Addressing potential challenges in cell based immunotherapies
Dr Emmett Schmidt
09:40

Combinational immunotherapy in oncology: increasing the effective targeting of neo-epitopes

 
  • PD-1 Antibodies have the potential to be a broad spectrum antineoplastic treatment both as monotherapy and in combination therapies
  • Discussing the efficacy and toxicity profiles of therapeutic combinations
  • Current opportunities, challenges and the potential for unforeseen side effects
  • Thoughts for the future for combination immunotherapy in oncology
Dr Marcelle Van Mechelen
10:10

Integrated Immune Monitoring Solutions for Preclinical and Clinical Development of Immunotherapeutics

  • Multicolor-cytometry to accelerate preclinical and clinical development of checkpoints inhibitors
  • Immune profiling of vaccines
  • Fit-for-purpose assays: Integration of scientific expertise and high-end technology in a quality system
10:40

Morning Break

IMMUNE RESPONSE AND BIOMARKERS: B-CELL & T-CELL ANALYSIS

Dr Paul Moore
11:40

Advanced development of innovative immunotherapeutics: in combination and exploiting the DART platform

 
  • Overview of current progress, lessons learned, and future prospects for the combination immunotherapy of cancer
  • Discussing how application of the DART platform leads to enhanced checkpoint blockade
  • Mechanisms by which anti-tumour immune responses can be evoked when employing the novel DART platform
Dr Bradley Garcia
12:10

High-resolution profiling of antibody responses to arrays of peptides

 
  • Applications in vaccines, oncology, autoimmune disorders, antibody discovery
12:25

High-throughput sequencing for the T Cell and B Cell repertoire profiling

 
  • Effectively employing high-throughput sequencing for advanced profiling
  • Exploiting computational tools for the profiling of T-cell and B-cells for therapeutic developments
Prof Farzin Farzaneh
12:40

Development of active immune therapies and therapeutic vaccination strategies for haematological malignancies

13:10

Networking Lunch & Poster Session

Dr Dafne Mueller
14:40

Improving the anti-tumor immune response through the use of bi-and trifunctional antibody-cytokine fusion proteins

 
  • Designing bi- and trifunctional antibody-fusion proteins with IL-15 and costimulatory members of the B7 and TNF superfamily
  • Sharing research which shows enhanced immune responsiveness in vitro and anti-tumour activity in a mouse model in vivo
  • Discussing mode of action employed
Dr Sai Reddy
15:10

Accuracy and prediction in antibody repertoire analysis 

 
  • Novel error and bias correction of antibody repertoire data
  • Combining repertoire analysis with machine learning methods for predicting antigen exposure and specificity 
  • Functional screening of antibody repertoires using mammalian surface display technology
15:45

Networking Break

Dr Ali M. Harandi
16:15

Adjuvant profiling and systems analysis of vaccine induced response to enhance correlates of protection of human vaccines

 
  • Learn opportunities offered by systems analysis of response to human vaccines and adjuvants to inform rational vaccine development
  • Discussing the significance of new biomarkers in vaccine development
  • Sharing ongoing efforts within EU financed research programmes
Dr Shruthi Naik
16:45

Oncolytic Virotherapy: A New Cornerstone for Immuno-Oncology

  • Using engineered viruses to help cure cancer
  • Testing combinations in various clinical stages to harness and enhance the body’s natural tumour-killing immune responses
17:15

Chair’s closing remarks followed by Meet & Greet with key speakers in the Exhibition Hall

last published: 06/Oct/17 08:25 GMT