A biochemist by training, Achim has been working with bispecific antibodies or ADCs and technology development for their effective screening. In one flavour, screening of such and further complex NBEs is realized applying versatile microfluidics and in part in conjunction with mammalian libraries enabling rapid antibody hit discovery and optimization.
PoC studies applying mammalian libraries for both antibody optimization (screening for manufacturability and selectivity) as well as microfluidics-assisted high throughput cellular binding or functional screening exemplify the versatility and powerful options when combining these two emerging technologies.